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LTBR信息

英文名称:Tumor necrosis factor receptor superfamily member 3
中文名称:肿瘤坏死因子受体超家族成员3
靶点别称:Lymphotoxin-beta receptor,Tumor necrosis factor receptor type III,LTBR,Tumor necrosis factor receptor superfamily member 3,D12S370,TNFRSF3,TNFCR,TNFR3,TNFR Superfamily, Member 3,Lymphotoxin B Receptor,LT-BETA-R,TNF-R-III,TNFR2-RP,TNF-RIII,TNFR-III,TNFR-RP,Lymphotoxin beta Receptor,Tumor necrosis factor C receptor,Tumor Necrosis Factor Receptor 2-Related Protein,Lymphotoxin Beta Receptor (TNFR Superfamily, Member 3)
上市药物数量:0
临床药物数量:0
最高研发阶段:终止

LTBR 分子别名

LTBR,D12S370,TNFCR,TNFR3,TNFRSF3,TNFRIII

LTBR 分子背景

Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.

LTBR 前沿进展

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