高活性轻松去除核酸残留(比活>1.00 x 10^6 U/mg);
高安全性(无菌、内毒素、HCP、支原体、外源病毒等检测);
高稳定性(经加速、冻融、实时稳定性验证);
完成 FDA DMF备案,支持临床/上市申报(备案编号:034936);
基于ACRO自主蛋白原料平台开发,产品性能和供货能力保障;
提供Premium 和GMP级别全能核酸酶,可实现从临床前开发到临床阶段的无缝过渡。
灵敏度高达2.733pg/mL,能够准确定量培养基上清中核酸酶的微量残留;
适配性强,除ACRO自产全能核酸酶外,还可兼容市面多家酶产品;
产品性能稳定,批内及批间精密度< 10%;
可免费提供完整方法学验证报告;
原料自产,产量高、货期短。
Cat. No. | Product description |
---|---|
BEE-N3116 | GENIUS™Nuclease DMF Filed |
NUE-S5119 | GENIUS™ Nuclease, premium grade |
GMP-NUES19 | GMP GENIUS™Nuclease DMF Filed |
Cat. No. | Product description |
---|---|
CRS-A016 | GENIUS™Nuclease ELISA Kit |
GENIUS™ Nuclease, premium grade(Cat. No. NUE-S5119)比竞品具有更高的生物活性(>1.2 x 10e6 units/mg)
GENIUS™ Nuclease, premium grade(Cat. No. NUE-S5119 )分别经4℃保存14d 和37℃加速48h后,活性依旧保持不变,具有高稳定性。
GENIUS™ Nuclease, premium grade(Cat. No. NUE-S5119)不同批次的生物保持一致,具有高批间一致性。
标准曲线是由ACRO自产的高纯度高灵敏的全能核酸酶系列稀释后经4-PL拟合得到,检测范围在39.06-2500pg/mL,R2可达到0.99
经检测,GENIUS™Nuclease ELISA Kit (Cat. No. CRS-A016 )可以用于检测不同品牌的全能核酸酶,且灵敏度基本一致。
Intra-Assay Precision: Twenty replicates of each of three samples containing different concentrations were tested in one assay. Within the detection range,the CV is less than 10%.
Inter-Assay Precision: Three replicates of each of three samples containing different concentrations were tested in three independent assays. Within the detection range,the CV is less than 10%.
Three parts of blank medium were added with three different concentrations of Nuclease, and the medium without Nuclease was used as background to calculate the recovery rate.