Siglec-10 靶点蛋白|抗体药物|临床药物信息

Siglec-10信息

英文名称：Sialic acid-binding Ig-like lectin 10
中文名称：唾液酸结合免疫球蛋白样凝集素-10
靶点别称：UNQ477/PRO940，SIGLEC10，Sialic Acid Binding Ig Like Lectin 10，Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7，Siglec-Like Protein 2，Siglec-Like Gene 2，SLG2，Sialic Acid-Binding Ig-Like Lectin 10，Sialic Acid Binding Ig-Like Lectin 10，Siglec-10，PRO940，MGC126774

上市药物数量：0
临床药物数量：3
最高研发阶段：临床三期

Siglec-10产品列表

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产品库

在线 (10)

物种

标签

属性

Protein (10)

标记

货号	物种	产品描述
SI0-HP2E5	Human	PE-Labeled Human Siglec-10 Protein, His Tag (recommended for neutralizing assay)
SI0-H5253	Human	Human Siglec-10 Protein, Fc Tag
SI0-H52H9	Human	Human Siglec-10 Protein, His Tag (MALS verified)
SI0-H525b	Human	Human Siglec-10 Protein, Mouse IgG2a Fc Tag, low endotoxin
SI0-M52H7	Mouse	Mouse Siglec-10 Protein, His Tag
SI0-H82E3	Human	Biotinylated Human Siglec-10 Protein, His,Avitag™
SI0-H82F6	Human	Biotinylated Human Siglec-10 Protein, Fc,Avitag™ (MALS verified)
SI0-C52H5	Cynomolgus	Cynomolgus Siglec-10 Protein, His Tag (MALS verified)
SI0-H5254	Human	Human Siglec-10 Protein, Fc Tag
SI0-H5255	Human	Human Siglec-10 Protein, Fc (L118A, G120A, E201A) Tag

SI0-M52H7|Mouse Siglec-10 Protein, His Tag

151XXXXXXX5

2人赞

用购买的Siglec10蛋白测了流式实验 siglec10能够和靶细胞有很好的结合结合是和唾液酸有相关性实验重复性高 ACro是值得信赖的生物公司
2021-09-01

SI0-H5253|Human Siglec-10 Protein, Fc Tag

180XXXXXXX7

2人赞

买这个主要目的是通过Elisa的方法检测我们的药物能否和该产品结合。通过摸索不同的包板浓度，达到了预期的目的。
2021-12-21

SI0-C52H5|Cynomolgus Siglec-10 Protein, His Tag (MALS verified)

181XXXXXXX2

1人赞

已经多次购买这个抗体，质量很好，给的QC报告和实验室自己做的一样，很匹配，图谱很清晰明了
2021-08-24

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Siglec-10 分子别名

SIGLEC10,MGC126774,PRO940,Siglec10,SLG2

Siglec-10 分子背景

The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-10 前沿进展

Siglec-10临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
AI-071	AI-071	临床一期	广州昂科免疫生物技术有限公司	新型冠状病毒肺炎, 肿瘤	详情
EXO-CD24		临床二期	Tel-Aviv Sourasky Medical Center	新型冠状病毒肺炎	详情
Efprezimod alfa	CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110	临床三期	Oncoimmune Inc	白血病, 造血干细胞移植, HIV感染, 实体瘤, 移植物抗宿主病, 新型冠状病毒肺炎, 骨髓增生异常综合征, 急性淋巴细胞白血病, 血脂障碍, 急性髓细胞样白血病, 黑色素瘤	详情

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Siglec-10