MICA 靶点蛋白|抗体药物|临床药物信息

> 【MICA】

MICA产品列表

筛选结果

产品库

在线 (2)

物种

Human (2)

标签

属性

Protein (2)

标记

Unconjugated (2)

货号	物种	产品描述	蛋白结构	纯度	活性
MIA-H5221	Human	Human MICA Protein, His Tag (MALS verified)
MIA-H5253	Human	Human MICA Protein, Fc Tag

MICA 分子别名

MIC-A

MICA 分子背景

MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.