MICA 靶点蛋白|抗体药物|临床药物信息

MICA信息

英文名称：MHC class I polypeptide-related sequence A
中文名称：
靶点别称：

上市药物数量：0
临床药物数量：2
最高研发阶段：临床一期

MICA产品列表

筛选结果

产品库

在线 (3)

物种

Human (3)

标签

属性

Protein (3)

标记

货号	物种	产品描述
MIA-H5221	Human	Human MICA Protein, His Tag (MALS verified)
MIA-H5253	Human	Human MICA Protein, Fc Tag
MIA-H82E6	Human	Biotinylated Human MICA Protein, His,Avitag™ (MALS verified)

MIA-H5221|Human MICA Protein, His Tag (MALS verified)

182XXXXXXX6

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2022-09-27

MICA 分子别名

MIC-A

MICA 分子背景

MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.

MICA 前沿进展

MICA临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
CLN-619	CLN-619	临床一期	PDI Therapeutics Inc	实体瘤	详情
FT-536	FT-536	临床一期	Fate Therapeutics Inc	实体瘤	详情
α3 MICA/B iNK cells (GT Biopharma/Fate Therapeutics)			Gt Biopharma Inc, Fate Therapeutics Inc		详情

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MICA