Glypican 3 靶点蛋白|抗体药物|临床药物信息

Glypican 3信息

英文名称：Glypican-3
中文名称：磷脂酰肌醇聚糖3
靶点别称：MXR7，OCI5，GPC3，Glypican-3，Glypican 3，Glypican Proteoglycan 3，GTR2-2，Secreted Glypican-3，OCI-5，SGBS1，DGSX，SGBS，SDYS，SGB，Intestinal protein OCI-5，Heparan Sulphate Proteoglycan

上市药物数量：0
临床药物数量：24
最高研发阶段：临床二期

Glypican 3产品列表

筛选结果

产品库

在线 (21)

物种

标签

属性

Protein (21)

标记

货号	物种	产品描述
GP3-H52H4	Human	Human Glypican 3 / GPC3 Protein, His Tag, premium grade
GP3-H82E5	Human	Biotinylated Human Glypican 3 / GPC3 Protein, His,Avitag™, premium grade
GP3-H5223	Human	Human Glypican 3 / GPC3 (S359F) Protein, His Tag, low endotoxin
GP3-C5225	Cynomolgus	Cynomolgus Glypican 3 / GPC3 Protein, His Tag
GP3-C5256	Cynomolgus	Cynomolgus Glypican 3 / GPC3 Protein, Fc Tag
GP3-C5259	Cynomolgus	Cynomolgus Glypican 3 / GPC3 Protein, Llama IgG2b Fc Tag, low endotoxin
GP3-H5257	Human	Human Glypican 3 / GPC3 Protein, Llama IgG2b Fc Tag, low endotoxin
GP3-H5258	Human	Human Glypican 3 / GPC3 Protein, Fc Tag, low endotoxin
GP3-H52H7	Human	Human Glypican 3 / GPC3 (S359F) Protein, His Tag, low endotoxin (MALS verified)
GP3-H52H8	Human	Human Glypican 3 / GPC3 (S495A, S509A) Protein, His Tag
GP3-H82E8	Human	Biotinylated Human Glypican 3 / GPC3 Protein, His,Avitag™, premium grade
GP3-HA2H5	Human	Alexa Fluor™ 488-Labeled Human Glypican 3 / GPC3 Protein, His TagStar Staining
GP3-HA2H7	Human	APC-Labeled Human Glypican 3 / GPC3 Protein, His TagStar Staining
GP3-HA2H9	Human	APC-Labeled Human Glypican 3 / GPC3 Protein, His Tag (Site-specific conjugation)
GP3-HF258	Human	FITC-Labeled Human Glypican 3 / GPC3 Protein, Fc Tag
GP3-HF2H1	Human	FITC-Labeled Human Glypican 3 / GPC3 Protein, His Tag
GP3-HP2E3	Human	PE-Labeled Human Glypican 3 / GPC3 Protein, His Tag (Site-specific conjugation)
GP3-HP2H9	Human	PE-Labeled Human Glypican 3 / GPC3 Protein, His TagStar Staining
GP3-M5254	Mouse	Mouse Glypican 3 / GPC3 Protein, Fc Tag
GP3-M52H3	Mouse	Mouse Glypican 3 / GPC3 Protein, His Tag
GP3-R52H7	Rat	Rat Glypican 3 / GPC3 Protein, His Tag

GP3-HF258|FITC-Labeled Human Glypican 3 / GPC3 Protein, Fc Tag

180XXXXXXX6

12人赞

GPC3目前也是实体瘤的一个热门靶点，购买这款产品，是用于CART细胞阳性率的检测，与我们自己纯化表达的蛋白（加hFc tag,需要用荧光标记的二抗），结果一致，不过这个不用染二抗，还是方便很多
2019-10-11

GP3-H52H4|Human Glypican 3 / GPC3 Protein, His Tag, premium grade

135XXXXXXX2

5人赞

使用抗原蛋白进行杂交瘤融合后阳性株的筛选，特异性好，空白对照背景很低，能有效快速帮助识别阳性克隆孔，推进实验。抗体冻干粉末状态，均匀外形好，效果佳，下单和配送服务都很好，推荐，现在基本抗体筛选都是用的acro的蛋白。
2021-08-17

GP3-H82E5|Biotinylated Human Glypican 3 / GPC3 Protein, His,Avitag™, premium grade

187XXXXXXX9

5人赞

使用该产品用于细胞转染率的检测，搭配荧光标记的二抗使用，可以检测细胞阳性率。在该抗体用量极少的情况下，也可得到准确满意的效果。
2022-03-04

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Glypican 3分子别名

GPC3,OCI5,Glypican-3,GTR2-2,MXR7,DGSX,SDYS ,SGB,SGBS,SGBS1

Glypican 3分子背景

Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.

Glypican 3临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
TAK-102	TAK-102	临床一期	Noile-Immune Biotech Inc	实体瘤, 肿瘤	详情
GLYCAR T cell therapy (Baylor College of Medicine)	GLYCAR	临床一期	贝勒医学院	肝癌, 横纹肌肉瘤, 横纹肌样瘤, 肝胚细胞瘤, 肾母细胞瘤, 脂肪肉瘤, 内胚窦瘤, 肝细胞癌	详情
GPC3-CAR-T cell therapy	CSG-GPC-3; CAR-GPC3 T-cell; GPC3-CAR/CSG-GPC3; anti-GPC-3 CAR T; KJgpc3-001; CT-011	临床一期	科济生物医药（上海）有限公司	实体瘤, 鳞状细胞癌, 肝细胞癌	详情
CAR-GPC3 T-cell (Drum Tower Hospital)		临床二期	南京鼓楼医院	肝细胞癌	详情
GPC3-CAR-T cell therapy(Origincell Medical Technology)	Ori-CAR-001	临床二期	原启生物科技（上海）有限责任公司	肝细胞癌	详情
Anti-GPC3 CAR T-cell therapy (Nanjing University)		临床一期	南京大学	肝细胞癌	详情
Anti-GPC3 chimeric antigen receptor T cell therapy (Hunan Zhaotai Yongren Biotech/Guangdong Zhaotai Invivo Biomedicine)		临床一期	湖南昭泰涌仁生物科技有限公司, 广东昭泰体内生物医药科技有限公司	鳞状细胞癌, 肝细胞癌	详情
CT-0180	CT-0180	临床一期	科济药业控股有限公司	肝细胞癌	详情
Anti-GPC3-IRDye800CW		临床阶段不明	中国科学院		详情
GPC-3298306	GPC-3298306	临床二期	National Cancer Center Of Japan	卵巢癌, 肝细胞癌	详情
IM-83 CAR-T cell therapy	IM-83	临床一期	北京艺妙神州医药科技有限公司	肝癌	详情
TC-CAR-031	TC-CAR-031; TC-CAR031	临床一期	浙江大学	肝细胞癌	详情
ERY-974	ERY-974	临床一期	中外制药株式会社	实体瘤, 肝细胞癌	详情
GPC3 CAR-T therapy (Hrain Biotechnology)		临床二期	上海恒润达生生物科技股份有限公司	肝细胞癌	详情
GPC3-T2 CAR-T cell therapy (The Second Affiliated Hospital of Guangzhou Medical University)		临床一期	广州医科大学附属第二医院	鳞状细胞癌, 肝细胞癌	详情
GPC3-targeted CAR-T (Peking University)		临床一期	北京大学	肝细胞癌	详情
CM-350	CM-350	临床二期	康诺亚生物医药科技（成都）有限公司	实体瘤	详情
B010-A	B010-A	临床一期	上海医药集团股份有限公司	肝细胞癌	详情
CAR (hYP7)-T cells (National Cancer Institute)		临床一期	美国国立癌症研究所	肝癌, 肝细胞癌	详情
CT0181	CT-0181	临床一期	科济药业控股有限公司	肝细胞癌	详情
Codrituzumab	GC-33; RG-7686; RO-5137382	临床一期	中外制药株式会社, 罗氏	实体瘤, 肝细胞癌	详情
TH-012(Bangentai Biomedical)	TH-012	临床一期	邦恩泰（山东）生物医药科技集团股份有限公司	胃癌, 胰腺癌	详情
ECT-204	ECT-204; JWATM-204	临床二期	Eureka Therapeutics Inc	肝癌, 肝细胞癌	详情
BOXR-1030	BOXR-1030	临床二期	Unum Therapeutics Inc	肝癌, Merkel细胞癌, 鳞状细胞癌, 肺癌, 黏液样脂肪肉瘤, 肝细胞癌	详情

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Glypican 3

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