Recombinant Proteins iso9001 ISO13485
搜索
 > 【Glypican 3】重组蛋白信息

Glypican 3信息

英文名称:Glypican-3
中文名称:磷脂酰肌醇聚糖3
靶点别称:OCI-5,SGBS1,DGSX,SGBS,SDYS,SGB,MXR7,OCI5,GPC3,Glypican-3,Glypican 3,Glypican Proteoglycan 3,GTR2-2,Secreted Glypican-3,Intestinal protein OCI-5,Heparan Sulphate Proteoglycan
上市药物数量:0
临床药物数量:10
最高研发阶段:临床二期

Glypican 3产品列表

 
评论(1)
GP3-HF258|FITC-Labeled Human Glypican 3 / GPC3 Protein, Fc Tag
  1. 180XXXXXXX6
  2. 3人赞
  3. GPC3目前也是实体瘤的一个热门靶点,购买这款产品,是用于CART细胞阳性率的检测,与我们自己纯化表达的蛋白(加hFc tag,需要用荧光标记的二抗),结果一致,不过这个不用染二抗,还是方便很多
  4. 2019-10-11
 

Glypican 3 Molecule Synonym Name

GPC3,OCI5,Glypican-3,GTR2-2,MXR7,DGSX,SDYS ,SGB,SGBS,SGBS1

Glypican 3 分子背景

Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.

Glypican 3 参考文献

Glypican 3临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Anti-GPC3 chimeric antigen receptor T cell therapy (Hunan Yongren Medical Innovation/Guangdong Zhaotai InVivo Biomedicine) 临床一期 湖南昭泰医疗集团 肝癌, 肺癌 详情
GPC-3298306 GPC-3298306 临床二期 National Cancer Center Of Japan 卵巢癌, 肝细胞癌
Anti-GPC3 CAR T-cell therapy (Nanjing University) 临床一期 南京大学 肝细胞癌 详情
GPC3-T2 CAR-T cell therapy (The Second Affiliated Hospital of Guangzhou Medical University) 临床一期 广州医科大学附属第二医院 鳞状细胞癌, 肝细胞癌
GLYCAR T cell therapy (Baylor College of Medicine) GLYCAR 临床一期 贝勒医学院 肝细胞癌 详情
MDX-1414 MDX-1414 临床一期 百时美施贵宝 肿瘤
Anti-GPC3 chimeric antigen receptor T cell therapy (Shanghai Genechem) 临床二期 上海吉凯基因医学科技股份有限公司 肝癌, 肝细胞癌 详情
ERY-974 ERY-974 临床一期 中外制药株式会社 实体瘤 详情
Codrituzumab GC-33; RG-7686; RO-5137382 临床二期 中外制药株式会社, 罗氏 肝细胞癌 详情
GPC3-CAR-T cell therapy CSG-GPC-3; KJgpc3-001; CAR-GPC3 T-cell; anti-GPC-3 CAR T; GPC3-CAR/CSG-GPC3 临床一期 科济生物医药(上海)有限公司 实体瘤, 鳞状细胞癌, 肝细胞癌 详情

消息提示

请输入您的联系方式,再点击提交!

确定