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CD31产品列表

产品库
物种
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CD1-H5224
Human
Human CD31 / PECAM-1 Protein, His Tag
CD1-H5258
Human
Human-PECAM1-CD31-Protein-C-Fc-Tag
 
评论(1)
CD1-H5258|Human CD31 / PECAM-1 Protein, Fc Tag
  1. 757XXXXXXX
  2. 0人赞
  3. Amazing customer service! Very prompt and received replies from multiple sources. Detailed CoA, which was highly appreciated. Used this protein to attach CD31 to Protein G dynabeads. Shipping was faster than anticipated and came packaged very nicely. I imagine this product could also be adhered to plates with high surface binding chemistry for use in assays where you measure cells adhering to CD31.
  4. 2021-11-14
 

CD31 分子别名

PECAM1,CD31,FLJ34100,FLJ58394

CD31 分子背景

Cluster of Differentiation 31 (CD31) is also known as Platelet endothelial cell adhesion molecule (PECAM-1), is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, osteoclasts, neutrophils, certain tumors, and is the only known member of the CAM family on platelets. CD31 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. CD31 plays a key role in removing aged neutrophils from the body. CD31 mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. In addition, it has been shown that CD31 expression is up-regulated by LPS stimulation, and might function as a feedback negative regulator of LPS inflammatory response in macrophages.

CD31 前沿进展

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