Complement C3 靶点蛋白|抗体药物|临床药物信息

Complement C3信息

英文名称：Complement C3
中文名称：补体C3
靶点别称：Complement C3，Complement Component C3a，Epididymis Secretory Sperm Binding Protein Li 62p，C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1，C3bc，C3adesArg，C3，Complement Component C3b，Complement Component 3，C3a Anaphylatoxin，Prepro-C3，CPAMD1，Acylation-Stimulating Protein Cleavage Product，HEL-S-62p，AHUS5，ARMD9，ASP，C3a，C3b

上市药物数量：1
临床药物数量：7
最高研发阶段：批准上市

Complement C3产品列表

筛选结果

产品库

在线 (4)

物种

标签

属性

Protein (4)

标记

货号	物种	产品描述
CO3-C52H5	Cynomolgus	Cynomolgus Complement C3 Protein, His Tag (MALS verified)
CO3-H52H3	Human	Human Complement C3 Protein, His Tag (MALS verified)
CO3-H82E8	Human	Biotinylated Human Complement C3 Protein, His,Avitag™ (MALS verified)
CO3-M52H4	Mouse	Mouse Complement C3 Protein, His Tag (MALS verified)

CO3-C52H5|Cynomolgus Complement C3 Protein, His Tag (MALS verified)

158XXXXXXX8

2人赞

Acro的蛋白包装精美、发货速度快，干冰充足，保证产品低温，防止蛋白降解，到货也会检测温度，非常认真负责。蛋白纯度高，稳定性好，用来做抗体亲和力检测，结果很好很稳定！已经多次回购，相比于竞品厂家性价比更高，值得信赖!!强烈推荐！！
2023-01-07

CO3-H82E8|Biotinylated Human Complement C3 Protein, His,Avitag™ (MALS verified)

158XXXXXXX8

2人赞

Acro公司产品包装很好、发货速度快，满满的干冰，保证了运输途中的低温度，防止蛋白降解。蛋白纯度高，用来做体外功能试验和亲和力检测，效果都很好！多次合作伙伴赞!!相比于其他厂家性价比高，值得信赖!墙裂推荐！
2022-12-22

CO3-H52H3|Human Complement C3 Protein, His Tag (MALS verified)

158XXXXXXX8

1人赞

Acro公司产品包装很好、发货速度快，满满的干冰，保证了运输途中的低温度，防止蛋白降解。蛋白纯度高，用来做体外功能试验和免疫动物免疫动物，效果都很好，抗体效价高！多次合作伙伴赞!!相比于其他厂家性价比高，值得信赖!!强烈推荐！！
2022-12-22

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Complement C3 分子别名

Complement C3,CPAMD1

Complement C3 分子背景

C3 is the major complement component serum. It is mainly synthesized by macrophages and liver. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. It is cleaved into two fragments, C3a and C3b. C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Complement C3 前沿进展

Complement C3上市药物信息

英文名称	中文名称	研发代码	研发阶段	公司	最早商品名	最早批准国家	最早适应症	最早批准公司	最早批准日期	适应症	临床试验
Pegcetacoplan		APL-2	批准上市	Apellis Pharmaceuticals Inc	Aspaveli, Empaveli	EU	阵发性血红蛋白尿症	Swedish Orphan Biovitrum Ab (Publ)	2021-05-14	运动神经元病, 肾脏移植排斥, 阵发性血红蛋白尿症, 免疫球蛋白a肾病, 膜性肾小球肾炎, 狼疮肾炎, 血栓性微血管病, 膜增生性肾小球肾炎, 自身免疫性溶血性贫血, 地图状萎缩, 肌萎缩性侧索硬化, 肾小球肾炎, 年龄相关性黄斑变性	详情

Complement C3临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
NGM-621	NGM-621	临床二期	Ngm Biopharmaceuticals Inc	新型冠状病毒肺炎, 地图状萎缩	详情
APL-9		临床二期	Apellis Pharmaceuticals Inc	新型冠状病毒肺炎, 成人呼吸窘迫综合征, 严重急性呼吸系统综合征, 冠状病毒感染	详情
Efdamrofusp alfa	IBI-302	临床二期	信达生物制药（苏州）有限公司	湿性黄斑变性, 糖尿病黄斑水肿, 年龄相关性黄斑变性	详情
Compstatin 40	AMY-101	临床二期	宾夕法尼亚大学	新型冠状病毒肺炎, 成人呼吸窘迫综合征, 牙龈炎	详情
ARO-C3	ARO-C3; ARO-C-3	临床一期	Arrowhead Pharmaceuticals Inc	免疫球蛋白a肾病, 阵发性血红蛋白尿症, 肾小球肾炎	详情
CG-001	CG-001	临床一期	成都康景生物科技有限公司	阵发性血红蛋白尿症, 自身免疫疾病	详情
ALXN-1820	ALXN-1820	临床二期	Alexion Pharmaceuticals Inc	镰状细胞血症	详情

会议日历

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Complement C3