登录 | 注册    关注公众号  
搜索

STEAP1信息

英文名称:Six-transmembrane epithelial antigen of the prostate 1
中文名称:前列腺六跨膜上皮抗原1
靶点别称:PRSS24,Six-transmembrane epithelial antigen of prostate 1,STEAP,STEAP1,STEAP Family Member 1,Six Transmembrane Epithelial Antigen Of The Prostate 1,STEAP1 Metalloreductase,Six Transmembrane Epithelial Antigen Of The Prostate,Metalloreductase STEAP1,EC 1.16.1.-,EC:1.16.1.-
上市药物数量:0
临床药物数量:2
最高研发阶段:临床二期

STEAP1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
ST1-H52H3
Human
Human STEAP1 Full Length Protein, His Tag (HEK293)
 
评论(0)
 

STEAP1 分子别名

STEAP1, PRSS24, STEAP

STEAP1 分子背景

Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.

STEAP1 前沿进展

STEAP1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
89Zr-DFO-MSTP2109A 临床二期 Memorial Sloan Kettering Cancer Center, 基因泰克 前列腺癌 详情
AMG-509 AMG-509 临床一期 安进, Xencor Inc 前列腺癌 详情

消息提示

请输入您的联系方式,再点击提交!

确定