DLL3 Molecule Synonym Name
Delta3,delta-like 3 (Drosophila),delta-like protein 3,DLL3,Pudgy,SCDO1,SCDO1delta3
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.
Tanaka K., et al. 2018, Lung Cancer., 115, 116-120.
Laura R. Saunders., et al. 2015, Sci Transl Med., 26, 7(302).
Zhang J., et al. 2017, Oncol Lett., 13(6), 4533-4539.