膜杰作
Star Staining
ViruStop
Aneuro
ComboX
ActiveMax
GENPower
ClinMax
> 【LRP-6】
LRP-6产品列表
产品库
物种
属性
| 货号 | 物种 | 产品描述 | 蛋白结构 | 纯度 | 活性 |
|---|---|---|---|---|---|
| LR6-H5253 |
 Human |
Human LRP-6 (20-630) Protein, Mouse IgG2a Fc Tag |
 |
  |
  |
| LR6-H82E7 |
Human |
Biotinylated Human LRP-6 (20-630) Protein, His,Avitag™ |
 |
 |
 |
评论(0)
LRP-6 分子别名
LRP-6,LRP6
LRP-6 分子背景
LRP6 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP5. Low-density lipoprotein receptor-related protein 6 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin.
