IL-22 靶点蛋白|抗体药物|临床药物信息

IL-22信息

英文名称：Interleukin-22
中文名称：白细胞介素-22
靶点别称：MGC79384，IL-TIF，ZCYTO18，UNQ3099/PRO10096，ILTIF，Cytokine Zcyto18，IL-22，IL22，Interleukin 22，IL-10-Related T-Cell-Derived Inducible Factor，IL-10-Related T-Cell-Derived-Inducible Factor，Interleukin-22，TIFIL-23，IL-D110，IL-21，TIFa，MGC79382

上市药物数量：0
临床药物数量：2
最高研发阶段：临床二期

IL-22产品列表

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产品库

在线 (2)

物种

Human (2)

标签

属性

Protein (2)

标记

货号	物种	产品描述	蛋白结构	纯度	活性
IL2-H524a	Human	Human IL-22 Protein, His Tag
IL2-H8247	Human	Biotinylated Human IL-22 Protein, His,Avitag™

IL-22分子别名

IL-22,IL-TIF,ZCYTO18

IL-22分子背景

Interleukin-22 (IL22) is also known as cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor (IL-TIF), which is belongs to the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2 receptor chains and further regulated by interactions with a soluble binding protein IL-22BP. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10.

IL-22临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
ARGX-112	LEO-138559; LP-0145; ARGX-112	临床二期	Leo Pharma Inc, Argenx Se	特应性皮炎	详情
AMT-126	AMT-126	临床一期	Applied Molecular Transport		详情

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IL-22

IL-22信息

IL-22产品列表

IL-22分子别名

IL-22分子背景

IL-22临床药物信息

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