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IL-22信息

英文名称:Interleukin-22
中文名称:白细胞介素-22
靶点别称:MGC79384,IL-TIF,ZCYTO18,UNQ3099/PRO10096,ILTIF,Cytokine Zcyto18,IL-22,IL22,Interleukin 22,IL-10-Related T-Cell-Derived Inducible Factor,IL-10-Related T-Cell-Derived-Inducible Factor,Interleukin-22,TIFIL-23,IL-D110,IL-21,TIFa,MGC79382
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

IL-22产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
IL2-H524a
Human
Human IL-22 Protein, His Tag
IL2-H8247
Human
Biotinylated Human IL-22 Protein, His,Avitag™
 
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IL-22 Molecule Synonym Name

IL-22,IL-TIF,ZCYTO18

IL-22 分子背景

Interleukin-22 (IL22) is also known as cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor (IL-TIF), which is belongs to the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2 receptor chains and further regulated by interactions with a soluble binding protein IL-22BP. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10.

IL-22 参考文献

IL-22临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
ARGX-112 LEO-138559; LP-0145; ARGX-112 临床一期 Leo Pharma Inc, Argen-X 特应性皮炎 详情

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