DLL4 靶点蛋白|抗体药物|临床药物信息

DLL4信息

英文名称：Delta-like protein 4
中文名称：δ样蛋白-4
靶点别称：Delta-Like Protein 4，Notch Ligand Delta-2，DLL4，Delta4，Delta-Like 4 (Drosophila)，Delta-Like 4 Homolog (Drosophila)，AOS6，Hdelta2，Notch Ligand DLL4，Delta Like Canonical Notch Ligand 4，Delta 4，Delta Ligand 4，Delta-Like 4 Protein，Drosophila Delta Homolog 4，Delta-Like 4 Homolog

上市药物数量：0
临床药物数量：3
最高研发阶段：临床三期

DLL4产品列表

筛选结果

产品库

在线 (3)

物种

Human (3)

标签

属性

Protein (3)

标记

货号	物种	产品描述
DL4-H5227	Human	Human DLL4 Protein, His Tag (MALS verified)
DL4-H5259	Human	Human DLL4 Protein, Fc Tag, premium grade
DL4-H82E6	Human	Biotinylated Human DLL4 Protein, His,Avitag™, premium grade

DL4-H5259|Human DLL4 Protein, Fc Tag, premium grade

906XXXXXXX

3人赞

This product was extremely useful for our T cell work. The vial it came in was easy to use (sometimes you'd be surprised how obtuse the packaging of a compound can be by certain companies) and has not lead to any issues with our research in many months. The only obstacle we have ever faced with adherent cells was as a result of our flat bottom plates being too old (and thus the coating wore off). So this product was more stable and consistent than the plates we put them on!
2022-07-24

DLL4 分子别名

DLL4,Delta4

DLL4 分子背景

Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.

DLL4 前沿进展

DLL4临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Dilpacimab	ABT-165; DVD-Ig ABT-165	临床一期	艾伯维	实体瘤, 肿瘤	详情
TR-009	NOV-1501; ABL001-ABL Bio; ABL-001-ABL Bio; ES-104; CTX-009	临床三期	Abl Bio Inc	胆管癌, 实体瘤, 直肠癌, 结肠癌, 肿瘤, 胆管上皮癌, 结直肠癌, 胆道癌, 胆囊癌	详情
Navicixizumab	OMP-305B83	临床三期	Oncomed Pharmaceuticals Inc	卵巢癌, 实体瘤, 胃癌, 三阴性乳腺癌, 结直肠癌, 腹膜癌, 输卵管癌	详情

会议日历

会议一览

DLL4