LIV-1 靶点蛋白|抗体药物|临床药物信息

LIV-1信息

英文名称：Zinc transporter ZIP6
中文名称：锌转运体ZIP6
靶点别称：LIV-1，LIV1，LIV-1 Protein， Estrogen Regulated，Solute Carrier Family 39 (Metal Ion Transporter)， Member 6，Zrt- and Irt-like protein 6，SLC39A6，Estrogen-regulated protein LIV-1，ZIP-6，Zinc transporter ZIP6，Solute Carrier Family 39 (Zinc Transporter)， Member 6，Solute carrier family 39 member 6

上市药物数量：0
临床药物数量：1
最高研发阶段：临床二期

LIV-1产品列表

筛选结果

产品库

在线 (10)

物种

标签

属性

Protein (10)

标记

货号	物种	产品描述
LV1-H5254	Human	Human LIV-1 / SLC39A6 Protein, Fc Tag (MALS verified)
LV1-H5223	Human	Human LIV-1 / SLC39A6 Protein, His Tag
LV1-M5223	Mouse	Mouse LIV-1 / SLC39A6 Protein, His Tag
LV1-C52H5	Cynomolgus	Cynomolgus LIV-1 / SLC39A6 Protein, His Tag
LV1-H82E3	Human	Biotinylated Human LIV-1 / SLC39A6 Protein, His,Avitag™
LV1-C82E5	Cynomolgus	Biotinylated Cynomolgus LIV-1 / SLC39A6 Protein, His,Avitag™
LV1-R52H9	Rat	Rat LIV-1 / SLC39A6 Protein, His Tag
LV1-C52H6	Cynomolgus	Cynomolgus LIV-1 / SLC39A6 Protein, His Tag, low endotoxin
LV1-H5255	Human	Human LIV-1 / SLC39A6 Protein, Fc Tag, low endotoxin
LV1-M52H4	Mouse	Mouse LIV-1 / SLC39A6 (C153A, C300A) Protein, His Tag (MALS verified)

LV1-H5223|Human LIV-1 / SLC39A6 Protein, His Tag

012XXXXXXX0

2人赞

When I was searching for this protein, there were not many options until I found ACRO. Very happy about various species as well as tag choices. ELISA results are reproducible and consistent. The delivery was fast whereas others may take longer. The product information is clear and comprehensive, which is very important for the research.
2022-05-02

LV1-C52H5|Cynomolgus LIV-1 / SLC39A6 Protein, His Tag

157XXXXXXX6

1人赞

我们之前买过这个蛋白，主要是用于ELISA实验，显示该蛋白质量可靠，与抗体结合很好，灵敏度也非常高。
2021-11-04

LV1-R52H9|Rat LIV-1 / SLC39A6 Protein, His Tag

157XXXXXXX6

0人赞

该蛋白纯度活性都符合我们ELISA实验要求。买过Acro的很多产品了，同一个蛋白有很多不同的标签蛋白可以选择，不同种属的也有，有很多选择的空间。
2021-11-14

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LIV-1 分子别名

SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6

LIV-1 分子背景

LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

LIV-1 前沿进展

LIV-1临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Ladiratuzumab vedotin	MK6440; MK-6440; SGN-LIV1A	临床二期	Seattle Genetics Inc, 默沙东	头颈部鳞状细胞癌, 食道癌, 胃癌, 小细胞肺癌, 三阴性乳腺癌, 前列腺癌, 乳腺癌, 食管鳞状细胞癌, 非小细胞肺癌, 腺癌, 黑色素瘤	详情

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LIV-1