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ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells)

ProductSizeAmount
ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells)2.5 mg2.5 × 10⁷ beads
10 mg (2.5 mg × 4)1.0 × 10⁸ beads

背景(Background)

ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells) are produced under sterile manufacturing conditions (ISO 5) , and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.

表达区间及表达系统(Source)

ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm with streptavidin on its surface and coupled with biotinylated Human VCAM-1 / CD106 Protein, expressed from human 293 cells (HEK293) and contains AA Phe 25 - Glu 698(Accession # P19320-1).

应用说明(Application)

ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells) is designed to synergistically activate Notch signaling in hematopoietic stem/progenitor cells (HSPCs). The synergistic interactions between Notch ligand Delta-like 4 and VCAM-1 are leveraged to enhance Notch signaling to support efficient T-cell lineage commitment, so the beads is recommended to use for in vitro production of induced pluripotent stem cell derived T cells coordinating with ActiveMax® Human DLL4 μBeads, premium grade (Cat. No. MBS-C013).

*We also carry ActiveMax® Streptavidin μBeads, premium grade (for cells)(Cat. No. MBS-C009),and it can be used for convenient preparation of your own sterile protein/antibody coupled beads for cell based assay, cell sorting and other applications. The ActiveMax® Streptavidin μBeads, premium grade can also be used together with other ActiveMax® μBeads, premium grade as Isotype control.

重构方法(Reconstitution)

See Certificate of Analysis (CoA) for detailed instruction.

存储(Storage)

This product is stable in storage under the following conditions: -20˚C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution.

Please avoid repeated freeze-thaw cycles after reconstitution. Immediate use after reconstitution is highly recommended.

无菌(Sterility)

The sterility testing was performed by membrane filtration method.

内毒素(Endotoxin)

Less than 0.002 EU per μg by the LAL method.

注意事项(Important Note)

This product is for research use only and not intended for therapeutic or in vivo diagnostic use.

制剂(Formulation)

Please contact us for detailed information.

Contact us for customized product form or formulation.

 

典型数据-Typical Data Please refer to Ds document for the assay protocol.

VCAM-1 TYPICAL DATA

Assay of human VCAM-1 / CD106 protein on the μBeads surface by Flow cytometry. The human VCAM-1 / CD106 protein conjugated on the μBeads (Cat. No. MBS-C019) surface were fluorescently stained using PE anti-human CD106 Antibody, analyzed by flow cytometry (QC tested).

 

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VCAM-1靶点信息
英文全称:Vascular cell adhesion molecule 1
中文全称:血管细胞粘附分子1
种类:Homo sapiens
上市药物数量:2详情
临床药物数量:1详情
最高研发阶段:批准上市
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