膜杰作
Star Staining
描述/背景（Background）
P16 is a member of the Ser/Thr protein kinase family. This protein is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers.
种属（Host Species）
Rabbit
克隆号（Clone）
4A7
适用方法（Application）
IHC
效价（Property）
1：1000
状态（State）
Liquid
阳性对照（Positive Control）
Human Tonsil Tissue
克隆类型（Clonality）
Monoclonal
分子别名（Synonym）
P16, CDK4
研究领域（Research Field）
Cancer Drug Targets
抗体来源（Source）
Rabbit
同种型（Isotype）
IgG
储存（Storage）
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
典型数据（Typical Data）
质控样本（Control Sample）
Immunohistochemical analysis of paraffin embedded Human Tonsil Tissue labelled with HGS-S315 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
肿瘤样本（Cancer Sample）
Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S315 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
