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 >  Antibody>CD56 >HGS-S251

Recombinant Monoclonal Anti-CD56 Antibody, Rabbit (3B6)

描述/背景(Background)

CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma.

种属(Host Species)

Rabbit

克隆号(Clone)

3B6

适用方法(Application)

IHC

效价(Property)

1:500

状态(State)

Liquid

阳性对照(Positive Control)

Human Tonsil Tissues

克隆类型(Clonality)

Monoclonal

分子别名(Synonym)

CD56, NCAM

研究领域(Research Field)

Cancer Drug Targets

抗体来源(Source)

Rabbit

同种型(Isotype)

IgG

储存(Storage)

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

 

典型数据(Typical Data)

质控样本(Control Sample)

CD56 CONTROL SAMPLE

Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S251 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

肿瘤样本(Cancer Sample)

CD56 CANCER SAMPLE

CD56 CANCER SAMPLE

CD56 CANCER SAMPLE

Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S251 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

 

前沿进展

 
 
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CD56靶点信息
英文全称:Neural cell adhesion molecule 1
中文全称:神经细胞粘附分子-1
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:4详情
最高研发阶段:临床二期
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