描述/背景(Background)
CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma.
种属(Host Species)
Rabbit
克隆号(Clone)
3B6
适用方法(Application)
IHC
效价(Property)
1:500
状态(State)
Liquid
阳性对照(Positive Control)
Human Tonsil Tissues
克隆类型(Clonality)
Monoclonal
分子别名(Synonym)
CD56, NCAM
研究领域(Research Field)
Cancer Drug Targets
抗体来源(Source)
Rabbit
同种型(Isotype)
IgG
储存(Storage)
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
典型数据(Typical Data)
质控样本(Control Sample)
Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S251 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
肿瘤样本(Cancer Sample)
Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S251 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.