膜杰作
Star Staining
ViruStop
Aneuro
ComboX
ActiveMax
GENPower
ClinMax
Siglec-15信息
英文名称：Sialic acid-binding Ig-like lectin 15
中文名称：唾液酸结合免疫球蛋白样凝集素-15
靶点别称：SIGLEC15，Sialic Acid Binding Ig Like Lectin 15，CD33 Antigen-Like 3，CD33L3，Sialic Acid-Binding Ig-Like Lectin 15，SIGLEC-15，HsT1361，CD33 Molecule-Like 3，Sialic Acid Binding Ig-Like Lectin 15
中文名称：唾液酸结合免疫球蛋白样凝集素-15
靶点别称：SIGLEC15，Sialic Acid Binding Ig Like Lectin 15，CD33 Antigen-Like 3，CD33L3，Sialic Acid-Binding Ig-Like Lectin 15，SIGLEC-15，HsT1361，CD33 Molecule-Like 3，Sialic Acid Binding Ig-Like Lectin 15
上市药物数量：0
临床药物数量：2
最高研发阶段：临床一期
临床药物数量：2
最高研发阶段：临床一期
Siglec-15产品列表
产品库
属性
评论(6)
SG5-H52H3|Human Siglec-15 / CD33L3 Protein, His Tag (MALS verified)
- 134XXXXXXX3
- 产品比较不错，价格方面也有优势，物流也是比较快，尤其品下边还有关于该产品的文献介绍，可以看出针对每一个靶点都是进过细心研究的。
- 2019-10-11
7人赞
SG5-H52H3|Human Siglec-15 / CD33L3 Protein, His Tag (MALS verified)
- 182XXXXXXX2
- 到货速度很快的产品，使用一款临床期的抗体与Human Siglec15做BLI实验，结果显而易见，具有很高的亲和力，解离速度很慢。
-
> - 2020-01-10
6人赞
SG5-M52H7|Mouse Siglec-15 / CD33L3 Protein, His Tag
- 182XXXXXXX2
- Mouse SIglec15与抗癌新药做亲和力测定，有一定的解离趋势，但是亲和力还有2E-9.
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> - 2020-01-10
6人赞
Siglec-15 分子别名
CD33 antigen-like 3,SIGLEC-15,CD33L3,sialic acid-binding Ig-like lectin 15,Siglec15,Siglec-15
Siglec-15 分子背景
Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
