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CD3 epsilon产品列表

 
评论(5)
CDE-H5223|Human CD3 epsilon Protein, His Tag (MALS verified)
  1. 152XXXXXXX4
  2. 4人赞
  3. 这款CD3e 大概是我用的最多和最久的一个抗原,此抗原已经“服务”过多个项目,之所以会回购,最多的原因还是因为抗原的稳定性好,批次间的一致性好,方法重现性好。
  4. 2020-04-07
CDE-H5256|Human CD3 epsilon Protein, Fc,His Tag
  1. 132XXXXXXX8
  2. 3人赞
  3. 紧跟双抗研发步伐,Anti-CD3 scFv-his形式的单抗筛选用该蛋白做ELISA和SPR均有良好的结果,用于scFv串联的无Fc的双抗也一样好用。
  4. >
  5. 2021-12-25
CDE-C5226|Cynomolgus CD3 epsilon Protein, His Tag (MALS verified)
  1. 132XXXXXXX8
  2. 3人赞
  3. 单独的his tag标签的蛋白主要用于杂交瘤上清阶段的筛选和鼠源抗体的鉴定,背景干净,活性稳定。
  4. >
  5. 2021-12-25
 

CD3 epsilon 分子别名

FLJ18683,T3E,TCRE,CD3E,CD3-epsilon

CD3 epsilon 分子背景

CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.

CD3 epsilon 前沿进展

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