登录 | 注册    微信公众号  
搜索
 > 【CD3 epsilon】

CD3 epsilon产品列表

 
评论(6)
CDE-M525a|Biotinylated Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a,Avitag™ (Clone: OKT3), Ultra-low endotoxin (MALS verified)
  1. 136XXXXXXX7
  2. 0人赞
  3. 本次实验在ELISA板上包被CD3E&CD3D (ACRO, Cat#CDD-H525W1),再结合梯度浓度的OKT3 (ACRO, Cat#CDE-M525a),结果显示和ACRO数据基本一致。ACRO产品质量值得信赖,我们的后续实验进行的也很顺利。
  4. >
  5. 2022-03-16
CDE-H5256|Human CD3 epsilon Protein, Fc,His Tag
  1. 132XXXXXXX8
  2. 2人赞
  3. 紧跟双抗研发步伐,Anti-CD3 scFv-his形式的单抗筛选用该蛋白做ELISA和SPR均有良好的结果,用于scFv串联的无Fc的双抗也一样好用。
  4. >
  5. 2021-12-25
CDE-C5226|Cynomolgus CD3 epsilon Protein, His Tag (MALS verified)
  1. 132XXXXXXX8
  2. 3人赞
  3. 单独的his tag标签的蛋白主要用于杂交瘤上清阶段的筛选和鼠源抗体的鉴定,背景干净,活性稳定。
  4. >
  5. 2021-12-25
 

CD3 epsilon 分子别名

FLJ18683,T3E,TCRE,CD3E,CD3-epsilon

CD3 epsilon 分子背景

CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.

CD3 epsilon 前沿进展

消息提示

请输入您的联系方式,再点击提交!

确定