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B7-H5信息

英文名称:V-domain Ig suppressor of T-cell activation
中文名称:T细胞活化的免疫球蛋白抑制V型结构域
靶点别称:Dies1,VSIR,V-Set Domain-Containing Immunoregulatory Receptor,DD1alpha,B7-H5,PD-1H,B7H5,GI24,Stress-induced secreted protein-1,PP2135,SISP1,UNQ730/PRO1412,V-type immunoglobulin domain-containing suppressor of T-cell activation,V-Set Immunoregulatory Receptor,V-Domain Ig Suppressor Of T Cell Activation,PDCD1 Homolog,C10orf54,Sisp-1,VISTA,Chromosome 10 Open Reading Frame 54,Stress Induced Secreted Protein 1,Platelet Receptor Gi24,Death Domain1alpha
上市药物数量:0
临床药物数量:3
最高研发阶段:临床一期

B7-H5产品列表

 
评论(6)
B75-H52H0|Human B7-H5 / Gi24 / VISTA Protein, His Tag (MALS verified)
  1. 188XXXXXXX0
  2. 0人赞
  3. ELisa实验中抗原的选择十分重要,抗原的质量改坏直接影响了整个实验的进展。这个试剂具有稳定的性质,可以得到可靠且专业的结果,对实验方法的建立都有着非常重要的作用
  4. 2022-04-22
B75-H52H0|Human B7-H5 / Gi24 / VISTA Protein, His Tag (MALS verified)
  1. 188XXXXXXX1
  2. 0人赞
  3. 感谢acro提供这麽好的产品,我们一直在用,产品批间非常稳定,对于我们的研发工作提供了非常大的帮助。如果有新产品,希望acro能多做宣传。
  4. 2022-04-21
B75-H52H0|Human B7-H5 / Gi24 / VISTA Protein, His Tag (MALS verified)
  1. 131XXXXXXX6
  2. 0人赞
  3. 我一般是不会主动给试剂做评价的,一是觉得没有什么意义二是觉得害怕自己不严谨的试验会对别人造成困扰。然后这试剂我是经过过了多次的试验之后才敢说的,值得购买,值得试用,相信我你会得到满意的结果!
  4. 2022-04-21
 

B7-H5 分子别名

B7-H5,SISP1,Gi24,VISTA

B7-H5 分子背景

Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

B7-H5 前沿进展

B7-H5临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Onvatilimab CI-8993; JNJ-61610588 临床一期 杨森, Immunext 实体瘤, 肿瘤 详情
HMBD-002 HMBD-002 临床一期 蜂鸟生物科技 实体瘤, 三阴性乳腺肿瘤, 非小细胞肺癌, 转移癌 详情
CA-170 AUPM-170; CA-170 临床一期 Aurigene 实体瘤 详情

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