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B7-H7信息

英文名称:HERV-H LTR-associating protein 2
中文名称:人类内源性逆转录病毒H长末端重复序列结合蛋白2
靶点别称:Human endogenous retrovirus-H long terminal repeat-associating protein 2,B7-H7,B7H7
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

B7-H7产品列表

 
评论(3)
B77-H5257|Human B7-H7 / HHLA2 Protein, Fc Tag (MALS verified)
  1. 185XXXXXXX0
  2. 1人赞
  3. 该产品用于药物发现高通量筛选,主要用于ELISA和FRET方法来进行高通量筛选,使用其他品牌的产品未测出活性, 用 ACRO的B7-H7与其他厂家的受体具有很好的亲和力,使我们建立稳定了的筛选体系。
  4. 2021-09-03
B77-H52H6|Human B7-H7 / HHLA2 Protein, His Tag (MALS verified)
  1. 151XXXXXXX5
  2. 0人赞
  3. 我们购买该蛋白是为了检测该蛋白和其他蛋白的亲和力,应用于spr实验,该蛋白和其他抗体之间的亲和力很好,应用起来没有太大的烦恼,说明书也很详细,非常贴心!
  4. 2022-08-10
B77-H52H5|Human B7-H7 / HHLA2 Protein, His Tag (MALS verified)
  1. 176XXXXXXX6
  2. 0人赞
  3. ACRO的此蛋白目前用于抗体筛选实验安排中,进行了ELISA Binding,Blocking实验中,曲线很好,数据稳定;
  4. 2021-09-03
 

B7-H7 分子别名

B7-H7,HHLA2,B7 Homolog 7

B7-H7 分子背景

B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.

B7-H7 前沿进展

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