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Protein A产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
MPC-A001
Recombinant
Protein A-coupled Magnetic Beads (recommended for MPCLIA)
ACRO质量管理体系
 
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Protein A 分子别名

RPA,Protein A

Protein A 分子背景

Protein A is a 40-60 kDa surface protein originally found in the cell wall of the bacteria Staphylococcus aureus (SPA). SPA binds proteins from many of mammalian species, most notably IgGs, and helps inhibit phagocytic engulfment and acts as an immunological disguise via this type of interaction, thus the bacteria will disrupts opsonization and phagocytosis. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. It couples to a wide variety of reporter molecules including fluorescent dyes, enzyme markers, biotin, colloidal gold and radioactive iodine without affecting the antibody binding site. Recombinant Protein A was developed to increase the specificity of the molecule for IgG and is widely used both in research and bioprocessing.

Protein A 前沿进展

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