ROR1 靶点蛋白|抗体药物|临床药物信息

ROR1信息

英文名称：Inactive tyrosine-protein kinase transmembrane receptor ROR1
中文名称：受体酪氨酸激酶样孤儿受体1
靶点别称：EC 2.7.10.1，Inactive tyrosine-protein kinase transmembrane receptor ROR1，NTRKR1，ROR1，Receptor Tyrosine Kinase Like Orphan Receptor 1，Neurotrophic Tyrosine Kinase， Receptor-Related 1，DJ537F10.1，ROR-1

上市药物数量：0
临床药物数量：8
最高研发阶段：临床三期

Licensing 项目合作

项目名称	适应症	项目阶段	合作需求
BPR202203	卵巢癌	PCC	寻求项目转让或者合作开发

ROR1产品列表

筛选结果

产品库

在线 (17)

物种

标签

属性

标记

货号	物种	产品描述
RO1-H522y	Human	Human / Cynomolgus / Rhesus macaque ROR1 Protein, His Tag (MALS verified)
RO1-H5222	Human / Cynomolgus / Rhesus macaque	Human / Cynomolgus / Rhesus macaque ROR1 (165-305, Frizzled domain) Protein, His Tag
RO1-H5250	Human	Human / Cynomolgus / Rhesus macaque ROR1 Protein, Fc Tag (MALS verified) DMF Filed
RO1-H5223	Human	Human / Cynomolgus / Rhesus macaque ROR1 (308-395, Kringle domain) Protein, His Tag (MALS verified)
RO1-H5221	Human / Cynomolgus / Rhesus macaque	Human / Cynomolgus / Rhesus macaque ROR1 (39-151, Ig-like domain) Protein, His Tag
RO1-M5221	Mouse	Mouse ROR1 Protein, His Tag
RO1-M5250	Mouse	Mouse ROR1 Protein, Fc Tag (MALS verified)
RO1-H82F4	Human	Biotinylated Human / Cynomolgus / Rhesus macaque ROR1 Protein, Fc,Avitag™
RO1-R5221	Rat	Rat ROR1 Protein, His Tag (MALS verified)
RO1-H821y	Human	Biotinylated Human / Cynomolgus / Rhesus macaque ROR1 Protein, Avitag™
RO1-H82E6	Human	Biotinylated Human / Cynomolgus / Rhesus macaque ROR1 Protein, His,Avitag™ (MALS verified)
MBR-K009	Human	Human ROR1-coupled Magnetic Beads
RO1-H5256	Human / Cynomolgus / Rhesus macaque	Human / Cynomolgus / Rhesus macaque ROR1 Protein, Mouse IgG2a Fc Tag
RO1-HF258	Human	FITC-Labeled Human ROR1 Protein, His Tag
RO1-HF253	Human	FITC-Labeled Human ROR1 Protein, Fc Tag
RO1-HP2E3	Human	PE-Labeled Human ROR1 Protein, His Tag (Site-specific conjugation)

RO1-H5250|Human / Cynomolgus / Rhesus macaque ROR1 Protein, Fc Tag (MALS verified) DMF Filed

188XXXXXXX5

3人赞

采购该蛋白，用于小鼠与羊驼的免疫，血清效价很好，且可以筛选到与ROR1受体+细胞亲和的binder，说明蛋白结构正确~
2021-11-21

RO1-H5223|Human / Cynomolgus / Rhesus macaque ROR1 (308-395, Kringle domain) Protein, His Tag (MALS verified)

185XXXXXXX3

1人赞

本部门采购RO1-H5223蛋白用于早期蛋白筛选，利用SPR对候选蛋白亲和力强弱进行筛选和对较优蛋白进行完整Affinity检测，用于专利申报等。实验结果显示，贵公司蛋白质量较好，能很好推进项目顺利进行。
2022-02-21

RO1-H522y|Human / Cynomolgus / Rhesus macaque ROR1 Protein, His Tag (MALS verified)

159XXXXXXX9

1人赞

订购不同批次的抗原用于ELISA实验，用于方法确认，经过验证不同批次间抗原稳定，质量可靠，值得信赖。
2021-08-12

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ROR1 分子别名

ROR1,NTRKR1

ROR1 分子背景

The biotinylated ROR1 protein was conjugated to streptavidin magnetic beads. This pre-coupled magnetic bead product can capture the anti-ROR1 antibody from various assay systems. The beads are in uniform size, narrow size distribution with large surface area and unique surface coating, which can help you get the best performance and highly reproducible results. This ROR1 coupled magnetic beads will bring great convenience with minimum non-specific binding and developed protocols. This ready-to-use product could greatly save your time and hassle.

ROR1 前沿进展

ROR1临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
HG-030	HG-030	临床一期	成都先导药物开发股份有限公司	实体瘤	详情
ROR1R-CAR		临床一期	德州大学安德森癌症中心, CLL的全球研究基金会联盟	白血病	详情
SIM-201	SIM-201; SIM-0201	临床一期	江苏先声药业有限公司	实体瘤	详情
NBE-002	NBE-002		Nbe-Therapeutics Ag		详情
LCB-71	CS-5001; LCB-71	临床一期	基石药业, Legochem Biosciences	B-细胞淋巴瘤, 实体瘤, 血液肿瘤	详情
NVG-111	NVG-111		NovalGen Ltd		详情
GNC-035 quadr-specific antibody（baili）	GNC-035	临床一期	四川百利药业有限责任公司	血液肿瘤, 实体瘤, 转移性乳腺癌	详情
LYL-797	LYL-797	临床一期	Lyell Immunopharma Inc	实体瘤, 三阴性乳腺肿瘤, 非小细胞肺癌	详情
Zilovertamab	UC-961	临床二期	加利福尼亚大学	卵巢癌, 套细胞淋巴瘤, 乳腺癌, 前列腺癌, 慢性淋巴细胞白血病	详情
Zilovertamab vedotin	VLS-101; MK-2140	临床三期	Velosbio, 默沙东, 默沙东研发（中国）有限公司	套细胞淋巴瘤, 非小细胞肺癌, 慢性淋巴细胞白血病, 急性髓细胞样白血病, T-细胞淋巴瘤, Burkitt淋巴瘤, 华氏巨球蛋白血症, 淋巴瘤, 乳腺癌, 急性淋巴细胞白血病, 血液肿瘤, 滤泡中心淋巴瘤, 胰腺癌, 三阴性乳腺肿瘤, 肿瘤, 弥漫性大B-细胞淋巴瘤, 胃癌, 卵巢癌, B-细胞淋巴瘤, 边缘带B细胞淋巴瘤	详情

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ROR1