Nectin-1 靶点蛋白|抗体药物|临床药物信息

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Protein (2)

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Unconjugated (2)

货号	物种	产品描述	蛋白结构	纯度	活性
PV1-H5223	Human	Human Nectin-1 / PVRL1 / CD111 Protein, His Tag
PV1-H5253	Human	Human Nectin-1 / PVRL1 / CD111 Protein, Fc Tag

Nectin-1 分子别名

PVRL1,Nectin-1,CD111,CLPED1,ED4,HIgR,HVEC,OFC7,PRR,PRR1,PVRR,PVRR1,SK-12

Nectin-1 分子背景

Poliovirus receptor-related protein 1 (PVRL1) is also known as Herpes virus entry mediator C (HveC), Herpesvirus Ig-like receptor (HIgR), Nectin-1, CD antigen CD111, PVRL1 / Nectin-1 / CD111 belongs to the nectin family. PVRL1 / Nectin-1 is a membrane protein with three extracellular immunoglobulin domains, a single transmembrane helix and a cytoplasmic tail. The protein can mediate Ca2+-independent cellular adhesion further characterizing it as IgSF cell adhesion molecule (IgSF CAM). PVRL1 is adhesion molecule found in a wide range of tissues. PVRL1 / Nectin-1 promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4.

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