膜杰作
Star Staining
ViruStop
Aneuro
ComboX
ActiveMax
GENPower
ClinMax
Mucin-1信息
英文名称：Mucin-1
中文名称：黏蛋白-1
靶点别称：PEM，Medullary Cystic Kidney Disease 1 (Autosomal Dominant)，Tumor Associated Epithelial Mucin，CD227 Antigen，H23 Antigen，MUC-1/SEC，ADMCKD1，Cancer antigen 15-3，Tumor-associated mucin，MUC1-alpha，MUC1-beta，MUC-1/X，MUC1/ZD，Mucin-1，ADMCKD，MCKD1，MAM6，MCKD，MCD，Polymorphic epithelial mucin，PUM，MUC1-NT，Episialin，CD227，MUC1-CT，MUC1，Mucin 1， Cell Surface Associated，Tumor-Associated Epithelial Membrane Antigen，Peanut-Reactive Urinary Mucin，Carcinoma-Associated Mucin，Krebs Von Den Lungen-6，CA 15-3，H23AG，MUC-1，
中文名称：黏蛋白-1
靶点别称：PEM，Medullary Cystic Kidney Disease 1 (Autosomal Dominant)，Tumor Associated Epithelial Mucin，CD227 Antigen，H23 Antigen，MUC-1/SEC，ADMCKD1，Cancer antigen 15-3，Tumor-associated mucin，MUC1-alpha，MUC1-beta，MUC-1/X，MUC1/ZD，Mucin-1，ADMCKD，MCKD1，MAM6，MCKD，MCD，Polymorphic epithelial mucin，PUM，MUC1-NT，Episialin，CD227，MUC1-CT，MUC1，Mucin 1， Cell Surface Associated，Tumor-Associated Epithelial Membrane Antigen，Peanut-Reactive Urinary Mucin，Carcinoma-Associated Mucin，Krebs Von Den Lungen-6，CA 15-3，H23AG，MUC-1，
上市药物数量：0
临床药物数量：19
最高研发阶段：临床二期
临床药物数量：19
最高研发阶段：临床二期
Mucin-1产品列表
产品库
属性
评论(2)
MU1-H82E5|Biotinylated Human Mucin-1 (890-1158) Protein, His,Avitag™
- 151XXXXXXX0
- Muc1结合了生物素的抗体，需要结合带有荧光标签的链霉亲和素使用，染色效果很好，流式结果也很好，注意是Muc1的哪个区短，选择相应克隆号！
- 2022-05-17
1人赞
MU1-H82E5|Biotinylated Human Mucin-1 (890-1158) Protein, His,Avitag™
- 183XXXXXXX5
- 一直购买的这个抗原，好多不常见的抗体抗原都可以在Acro买到，从没有失望过，而且实验结果很好，会一直购买，也会推荐给身边的同学和同事
- 2022-07-08
1人赞
Mucin-1 分子别名
Mucin 1,MUC1,CD227,EMA,H23AG,KL-6,MAM6,MUC-1,SEC,MUC-1,X,MUC1,ZD,PEM,PEMT,PUM,CA15-3,Episialin
Mucin-1 分子背景
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
Mucin-1 前沿进展
Mucin-1临床药物信息
| 英文名称 | 研发代码 | 研发阶段 | 公司 | 适应症 | 临床试验 |
|---|---|---|---|---|---|
| Anti-MUC1 CAR T cell (Guangzhou Anjie Biomedical) | 临床二期 | 广州安捷生物医学技术有限公司 | 食道癌, 前列腺癌, 非小细胞肺癌 | 详情 | |
| MUC1-Poly-ICLC | MUC1-poly-ICLC | 临床二期 | University Of Pittsburgh | 结直肠癌, 非小细胞肺癌 | 详情 |
| Recombinant HSP-MUC1 fusion protein (Newsummit) | 临床一期 | 上海新生源医药集团有限公司 | 乳腺癌 | 详情 | |
| Anti-MUC1 CAR T-cell therapy (Guangzhou Anjie Biomedical Technology/University of Technology Sydney) | 临床二期 | 广东药科大学附属第一医院, 广州安捷生物医学技术有限公司, University of Sydney | 非小细胞肺癌 | 详情 | |
| Anti MUC 1 chimeric antigen receptor T cell therapy (Innovative Cellular) | 临床一期 | 上海斯丹赛生物技术有限公司 | 胰腺癌, 乳腺癌, 肺癌 | 详情 | |
| Anti-MUC1 monoclonal antibody (OncoQuest) | AR20.5; mAb-AR20.5; Anti-MUC1 AR20.5 | 临床二期 | Altarex | 胰腺癌 | 详情 |
| ICTCAR-046 | ICTCAR-046 | 临床阶段不明 | 上海斯丹赛生物技术有限公司 | 胰腺癌 | 详情 |
| M-1231 | M-1231 | Emd Serono Research & Development Institute Inc, 默克雪兰诺 | 详情 | ||
| BromAc | Mucpharm Pty Ltd | 详情 | |||
| 90Y Clivatuzumab Tetraxetan | IMMU-107; 90Y-hPAM4; 90hY-PAM4 | Immunomedics Inc | 详情 | ||
| Cantuzumab ravtansine | Immunogen Inc | 详情 | |||
| P-MUC1C-ALLO1 | P-MUC1C-ALLO1; P-MUC1C-101 | 临床一期 | Poseida Therapeutics | 实体瘤 | 详情 |
| Anti-MUC1 CAR-T cell therapy (PersonGen) | 博生吉医药科技（苏州）有限公司 | 详情 | |||
| Monoclonal antibody HMFG1 | R-1550; AS-1402; BTH-1704; HuHMFG-1 | Cancer Research Uk | 详情 | ||
| GO-2032c | GO-203-2C | 临床二期 | Genus Oncology Llc, 丹娜法伯癌症研究院 | 急性髓细胞样白血病 | 详情 |
| TG-4010 | VV-MUC-IL2; TG-4010 | Transgene | 详情 | ||
| Adenoviral MUC1 vaccine (Etubics) | ETBX-061; Ad5-MUC1 | Etubics Corporation | 详情 | ||
| huMNC2-CAR44 | huMNC2-CAR44 | Minerva Biotechnologies | 详情 | ||
| Gatipotuzumab | GT-MAB-2.5-GEX | 临床一期 | Nemod | 实体瘤, 卵巢上皮癌, 腹膜癌, 输卵管癌 | 详情 |
| CART-TnMUC1 | 临床一期 | University Of Minnesota, 宾夕法尼亚大学 | 卵巢癌, 三阴性乳腺肿瘤, 多发性骨髓瘤, 胰腺导管癌, 输卵管癌, 非小细胞肺癌 | 详情 | |
| Cancer vaccine (BN ImmunoTherapeutics/National Cancer Institute) | CVAC-301; CV-301 | 临床二期 | Therion Biologics | 胰腺癌, 膀胱癌, 结直肠癌, 非小细胞肺癌 | 详情 |
| DXC-005 | DXC-005 | 临床一期 | 杭州多禧生物科技有限公司 | 实体瘤 | 详情 |
