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Fc epsilon RI alpha信息

英文名称:IgE Fc receptor, alpha-subunit
中文名称:IgE-Fc片段受体α亚基
靶点别称:Fc Fragment Of IgE, High Affinity I, Receptor For; Alpha Polypeptide,FCE1A,IgE Fc receptor subunit alpha,Fc-epsilon RI-alpha,FCER1A,Fc Fragment Of IgE Receptor Ia,Fc Fragment Of IgE, High Affinity I, Receptor For,Alpha Polypeptide,Fc Epsilon Receptor Ia,FcERI,Immunoglobulin E Receptor, High-Affinity, Of Mast Cells, Alpha Polypeptide,High Affinity Immunoglobulin Epsilon Receptor Alpha-Subunit,High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha,Fc IgE Receptor, Alpha Polypeptide,Fc Epsilon
上市药物数量:1
临床药物数量:0
最高研发阶段:批准上市

Fc epsilon RI alpha产品列表

 
评论(1)
FCA-H5228|Human Fc epsilon RI alpha Protein, His Tag (MALS verified)
  1. 189XXXXXXX3
  2. 0人赞
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  4. 2022-06-07
 

Fc epsilon RI alpha 分子别名

FCER1A,FCE1A,FcERI

Fc epsilon RI alpha 分子背景

High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fc-epsilon RI-alpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Ig-like (immunoglobulin-like) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.

Fc epsilon RI alpha 前沿进展

Fc epsilon RI alpha上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验
Benzylpenicilloyl Polylysine 青霉烯酰聚赖氨酸 批准上市 Allerquest Llc Pre-pen United States 过敏反应, 诊断剂 Allerquest Inc 1974-07-25 过敏反应, 诊断剂 详情

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