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CD2信息

英文名称:T-cell surface antigen CD2
中文名称:T细胞表面抗原CD2
靶点别称:T11,T-Cell Surface Antigen CD2,LFA-2,CD2 Antigens,CD2,LFA-3 Receptor,CD2 Molecule,Rosette Receptor,SRBC,CD2 Antigen,CD2 Antigen (P50), Sheep Red Blood Cell Receptor,T-Cell Surface Antigen T11/Leu-5,Lymphocyte-Function Antigen-2,Erythrocyte Receptor
上市药物数量:0
临床药物数量:3
最高研发阶段:临床二期

CD2 分子别名

CD2,SRBC,LFA-2,T11

CD2 分子背景

T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5 and SRBC, is a single-pass type I membrane protein found on the surface of T cells and natural killer (NK) cells. CD2 is a member of the immunoglobulin superfamily. CD2 / SRBC contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD2 / SRBC interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3 / CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections.

CD2 前沿进展

CD2临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
SBT-11-5301 SBT115301 临床一期 Sonoma Biotherapeutics Inc 自身免疫疾病 详情
PIT-565 PIT-565 临床一期 诺华制药 非霍奇金淋巴瘤, 急性髓细胞样白血病 详情
Siplizumab MEDI-507; TCD-601 临床二期 Catholic University Of Louvain, Itb-Med Llc 肾脏移植排斥, 白血病, 一型糖尿病, 骨髓增生异常综合征, 肿瘤, 肾脏疾病, 移植物抗宿主病, 多发性骨髓瘤, 银屑病, 淋巴瘤, T-细胞淋巴瘤, 终末期肾脏病 详情

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