CADM3 分子别名
CADM3,synCAM3,IGSF4B,BIgR,NECL1,TSLL1
CADM3 分子背景
Cell adhesion molecule 3 (CADM3) is also known as Synaptic cell adhesion molecule 3 (SynCAM3), Immunoglobulin superfamily member 4B (IgSF4B), Brain immunoglobulin receptor (BIgR), Nectin-like protein 1 (NECL-1), TSLC1-like protein 1 (TSLL1), which belongs to the nectin family. CADM3 contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain.The isoform 1 is expressed mainly in adult and fetal brain and isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum. CADM3 involved in the cell-cell adhesion and has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. CADM3 / SynCAM3 interaction with EPB41L1 may regulate structure or function of cell-cell junctions.
CADM3 前沿进展
- Fukuhara H., et al., 2001, Oncogene 20:5401-5407.
- Zhou Y., et al., 2005, Biochim. Biophys. Acta 1669:142-154.
- Gao J., et al., 2008, Biochim. Biophys. Acta 1778:1429-1435.
- Dong X., et al., 2006, J. Biol. Chem. 281:10610-10617.
膜杰作
Star Staining
Aneuro
ComboX
ActiveMax
GENPower
ClinMax
Star Ribbon
