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latent GDF-8信息

英文名称:Growth/differentiation factor 8
中文名称:生长分化因子-8
靶点别称:MSTN,GDF-8,GDF8,Growth Differentiation Factor 8,MSLHP,Myostatin,Growth/Differentiation Factor 8
上市药物数量:0
临床药物数量:4
最高研发阶段:临床三期

latent GDF-8产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
GD8-H5243
Human
Human latent GDF-8 Protein, His Tag (MALS verified)
 
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latent GDF-8 分子别名

latent GDF-8, GDF-8, Myostatin, GDF8, MSTN, Growth/differentiation factor 8

latent GDF-8 分子背景

Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions. GDF8 acts as a negative regulator of skeletal muscle growth and differentiation. In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.

latent GDF-8 前沿进展

latent GDF-8临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
AAV1-FS344 AAV1-Follistatin; AAV1-FS344 临床二期 Nationwide Children'S Hospital 包涵体肌炎, 杜氏肌营养不良症 详情
RO-7204239 GYM-329; RO-7204239; RG-6237; RG-70240 罗氏, 中外制药株式会社 详情
Ramatercept ACE-031; RAP-031; HGT-4510 Acceleron 详情
Apitegromab SRK-015 Scholar Rock 详情
Domagrozumab PF-6252616; PF-06252616 辉瑞 详情
Talditercept alfa RO-7239361; BMS-986089; RG-6206; BHV-2000 临床三期 百时美施贵宝 杜氏肌营养不良症, 神经肌肉疾病, 脊髓性肌萎缩 详情

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