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 > 【CCR8】

CCR8信息

英文名称:C-C chemokine receptor type 8
中文名称:CC趋化因子受体8型
靶点别称:Chemokine (C-C) Receptor 8,CC Chemokine Receptor 8,CDw198 Antigen,C-C CKR-8,CC-CKR-8,CCR-8,CMKBRL2,C-C Motif Chemokine Receptor 8,CC chemokine receptor CHEMR1,C-C chemokine receptor type 8,Chemokine (C-C Motif) Receptor 8,C-C Chemokine Receptor Type 8,CC Chemokine Receptor CHEMR1,Chemokine Receptor-Like 1,Chemokine (C-C) Receptor-Like 2,CC-Chemokine Receptor Chemr1,CD_antigen=CDw198,Chemokine receptor-like 1,CKRL1,CKR-L1,CMKBR8,GPRCY6,GPR-CY6,TER1,CDw198,CY6
上市药物数量:0
临床药物数量:8
最高研发阶段:临床二期

Licensing 项目合作

项目名称 适应症 项目阶段 合作需求
BSW202202 实体瘤 临床前 序列授权或寻求项目转让

CCR8产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
CC8-H52P4
Human
Human CCR8 Full Length Protein-VLP (HEK293)
ACRO质量管理体系
 
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CCR8 分子别名

CC chemokine receptor 8,CD198,,ChemR1,CKRL1,CKR-L1,CKRL1,CY6,GPRCL1,GPRCY6,GPR-CY6,TER-1

CCR8 分子背景

This entry represents CC chemokine receptor 8 (CCR8), which it is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs). CCR8 is associated with Th2 lymphocytes, which are critical for allergy, and has a role in lymphocyte activation, migration, proliferation and differentiation and in allergic diseases. CCR8 binds to CCL1 (also known as I-309) and to CCL16 (also known as liver expressed chemokine). It also exhibits a high affinity for three chemokines of viral origin: vMIP-I, vMIP-II and vMCC-I.

CCR8 前沿进展

CCR8临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
BMS-986340 BMS-986340 临床二期 Eeig Bristol-Myers Squibb Manufacturing Company Bristol-Myers Squibb Srl 头颈部鳞状细胞癌, 食道癌, 肿瘤, 结直肠癌, 非小细胞肺癌, 宫颈癌 详情
BAY-3375968 BAY-3375968 临床一期 拜耳 实体瘤, 肿瘤 详情
IPG-7236 IPG-7236; IPG-007 临床一期 南京艾美斐生物医药科技有限公司 实体瘤, 特应性皮炎 详情
JTX-1811 JTX-1811; GS-1811 临床一期 Jounce Therapeutics Inc 实体瘤 详情
S-531011 S-531011 临床二期 Shionogi Inc 实体瘤 详情
CM-369 CM-369 临床一期 北京天诺健成医药科技有限公司 实体瘤 详情
SRF-114 SRF-114 临床二期 Surface Oncology Inc 实体瘤, 头颈部鳞状细胞癌, 肿瘤 详情
LM-108 LM-108 临床二期 礼新医药科技(上海)有限公司 实体瘤 详情

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