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PTK7信息

英文名称:Protein-tyrosine kinase 7
中文名称:蛋白酪氨酸激酶-7
靶点别称:Colon carcinoma kinase 4,Inactive tyrosine-protein kinase 7,Tyrosine-protein kinase-like 7,CCK-4,PTK7,Protein Tyrosine Kinase 7 (Inactive),Pseudo Tyrosine Kinase Receptor 7,PTK7 Protein Tyrosine Kinase 7,CCK4,Protein-Tyrosine Kinase 7,Protein Tyrosine Kinase 7
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

PTK7产品列表

 
评论(3)
PT7-H5253|Human PTK7 / CCK4 Protein, Fc Tag (MALS verified)
  1. 153XXXXXXX9
  2. 1人赞
  3. 此蛋白亲和力特别好,而且比较稳定,在推荐的条件下进行溶解处理,使用时不同批次之间差异很小,在ELISA实验中,不管是用于包被还是标准品都有很好的重现性,后续还会继续使用,而且也会尝试其他蛋白。protocal也很详细,还有赠品,物流也快。
  4. >
  5. 2021-08-23
PT7-H52H3|Human PTK7 / CCK4 Protein, His Tag (MALS verified)
  1. 183XXXXXXX6
  2. 0人赞
  3. 经SPR验证,测单价亲和力,抗人FC芯片,load稀释后抗体,加入稀释后的PTK7,His tag,亲和力常数为4 nM。
  4. >
  5. 2022-07-21
PT7-H82E5|Biotinylated Human PTK7 / CCK4 protein, His,Avitag™ (MALS verified)
  1. 198XXXXXXX6
  2. 0人赞
  3. 主要用于筛选特定的抗原决定簇,来制定特定的抗体,使用起来很方便,希望下次配送更快点就好啦,有时候用着会着急,由于实验室不可以带手机就没有拍照
  4. 2022-05-19
 

PTK7 分子别名

PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7

PTK7 分子背景

PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

PTK7 前沿进展

PTK7临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Cofetuzumab Pelidotin PTK7-ADC; PF-6647020; PF-06647020; PF-7020; hu-24; ABBV-647; Anti-PTK7 ADC; h6M24-vc0101; PF-06523435 临床一期 艾伯维, Stemcentrx 肿瘤, 非小细胞肺癌 详情

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