PTK7 靶点蛋白|抗体药物|临床药物信息

PTK7信息

英文名称：Protein-tyrosine kinase 7
中文名称：蛋白酪氨酸激酶-7
靶点别称：Colon carcinoma kinase 4，Inactive tyrosine-protein kinase 7，Tyrosine-protein kinase-like 7，CCK-4，PTK7，Protein Tyrosine Kinase 7 (Inactive)，Pseudo Tyrosine Kinase Receptor 7，PTK7 Protein Tyrosine Kinase 7，CCK4，Protein-Tyrosine Kinase 7，Protein Tyrosine Kinase 7

上市药物数量：0
临床药物数量：1
最高研发阶段：临床一期

PTK7产品列表

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在线 (8)

物种

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属性

Protein (8)

标记

货号	物种	产品描述
PT7-H82E5	Human	Biotinylated Human PTK7 / CCK4 protein, His,Avitag™ (MALS verified)
PT7-H52H3	Human	Human PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-M52H3	Mouse	Mouse PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-H5253	Human	Human PTK7 / CCK4 Protein, Fc Tag (MALS verified)
PT7-C52H3	Cynomolgus / Rhesus macaque	Cynomolgus / Rhesus macaque PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-R52H4	Rabbit	Rabbit PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-R5255	Rat	Rat PTK7 / CCK4 Protein, Fc Tag
PT7-R52H6	Rat	Rat PTK7 / CCK4 Protein, His Tag (MALS verified)

PT7-H5253|Human PTK7 / CCK4 Protein, Fc Tag (MALS verified)

153XXXXXXX9

1人赞

此蛋白亲和力特别好，而且比较稳定，在推荐的条件下进行溶解处理，使用时不同批次之间差异很小，在ELISA实验中，不管是用于包被还是标准品都有很好的重现性，后续还会继续使用，而且也会尝试其他蛋白。protocal也很详细，还有赠品，物流也快。
>
2021-08-23

PT7-H52H3|Human PTK7 / CCK4 Protein, His Tag (MALS verified)

183XXXXXXX6

0人赞

经SPR验证，测单价亲和力，抗人FC芯片，load稀释后抗体，加入稀释后的PTK7,His tag，亲和力常数为4 nM。
>
2022-07-21

PT7-H52H3|Human PTK7 / CCK4 Protein, His Tag (MALS verified)

188XXXXXXX9

0人赞

此蛋白亲和力特别好，而且比较稳定，在推荐的条件下进行溶解处理，使用时不同批次之间差异很小，在ELISA实验中，不管是用于包被还是标准品都有很好的重现性，后续还会继续使用，而且也会尝试其他蛋白。protocal也很详细，还有赠品，物流也快。
2022-08-27

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PTK7 分子别名

PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7

PTK7 分子背景

PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

PTK7 前沿进展

PTK7临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Cofetuzumab Pelidotin	PF-06647020; PF-6647020; PTK7-ADC; PF-06523435; PF-7020; hu-24; ABBV-647; Anti-PTK7 ADC; h6M24-vc0101	临床一期	Stemcentrx Inc, 艾伯维	肿瘤, 非小细胞肺癌	详情

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PTK7