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SIRP alphaV2产品列表

 
评论(7)
SI2-H82W8|Biotinylated Human SIRP alphaV2 / CD172a Protein, His,Avitag™
  1. 177XXXXXXX7
  2. 0人赞
  3. 每次买蛋白都是在acro,这次购买human-bio-cd172aV2,用于检测抗体间表位竞争关系。
  4. >
  5. 2021-11-24
SI2-H52H9|Human SIRP alphaV2 / CD172a Protein, His Tag
  1. 177XXXXXXX7
  2. 0人赞
  3. 人源CD172a抗原,带HIS标签,octect仪器使用proA传感器结合抗原,检测抗体抗原结合强弱,筛选抗体。
  4. >
  5. 2021-11-10
SI2-H82W8|Biotinylated Human SIRP alphaV2 / CD172a Protein, His,Avitag™
  1. 152XXXXXXX0
  2. 0人赞
  3. 我们公司购买了Biotinylated Mouse SIRP alpha / CD172a Protein, His,Avitag™,主要目的是为了做免疫,从流式结果来看,还是不错的,已经反复试验过了,物流速度也很快,说明书很详细,销售人员也很专业。
  4. 2022-01-20
 

SIRP alphaV2 分子别名

SHPS1,SIRPA,CD172A,BIT,MFR,MYD1,P84,PTPNS1

SIRP alphaV2 分子背景

Tyrosine-protein phosphatase non-receptor type substrate 1 (SHPS1) is also known as CD172 antigen-like family member A (CD172a), Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha (SIRPA or SIRP alpha) or p84, is a member of the SIRP family, and also belongs to the immunoglobulin superfamily. SIRP alpha is Ubiquitous and highly expressed in brain. SIRPA / CD172a is immunoglobulin-like cell surface receptor for CD47 and acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRPA / SHPS-1 supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment and may play a key role in intracellular signaling during synaptogenesis and in synaptic function By similarity. SIRPA / MyD1 involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin and mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.

SIRP alphaV2 前沿进展

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