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Human NKp46 / NCR1 / CD335 Protein, Fc Tag

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分子别名(Synonym)

NCR1,LY94,CD335,NK-p46,hNKp46

表达区间及表达系统(Source)

Human NKp46 Protein, Fc Tag (NC1-H5259) is expressed from human 293 cells (HEK293). It contains AA His 129 - Thr 211 (Accession # O76036-1).

Predicted N-terminus: His 129

蛋白结构(Molecular Characterization)

NKp46 Structure

This protein carries a human IgG1 Fc tag at the C-terminus.

The protein has a calculated MW of 35.8 kDa .

制剂(Formulation)

Please contact us for detailed information.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

背景(Background)

Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

 

前沿进展

 
 
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NKp46靶点信息
英文全称:Natural cytotoxicity triggering receptor 1
中文全称:
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:3详情
最高研发阶段:临床二期
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