背景(Background)
MET is a tyrosine kinase receptor for the hepatocyte growth factor. It is linked to functions such as cell proliferation, scattering, morphogenesis, and survival. Ligand binding at the cell surface induces autophosphorylation of MET that provides docking sites for downstream signaling molecules. The C-MET IHC 1A1 Kit is a quick assay to detect C-MET across tumors to identify patients eligible for multiple targeted therapies. Kit product are manufactured in a dedicated GMP facility and are compliant with our ISO 13485 quality management system.
产品描述(Background)
Assay Type | Immunohistochemistry |
Analyte | C-MET |
Format | 2ml/7.5ml/30ml |
Reactivity | Human |
Species | Rabbit |
Regulatory Status | RUO |
Applicable Platform | LEICA BOND III |
组分(Materials Provided)
Recombinant Monoclonal Anti-C-MET Antibody, Rabbit (1A1)
Antibody diluent
应用说明(Application)
The kit is developed for use in the C-MET protein in the formalin-fixed, paraffin-embedded tissue. It is indicated as an aid in the assessment of C-MET expression in human tissues.
状态(State)
Liquid
存储(Storage)
Stored at 2°C to 8°C.
质控样本(Control Sample)
Use ACRO C-MET 1A1 kit to stain human colorectal cancer tissue, positive cell membrane specific positive staining (staining intensity ≥ 1), no non-specific staining (staining intensity < 1) , no background staining (staining intensity < 1).
肿瘤样本(Cancer Sample)
扩展性(Extensibility)
ACRO C-MET 1A1 kit expandable test: lung cancer, colorectal cancer, head and neck squamous cell cancer, liver cancer, gastric cancer.
Use C-MET 1A1 kit to stain lung cancer, colorectal cancer, head and neck squamous cell cancer, liver cancer, gastric cancer tissue samples respectively.