膜杰作
Star Staining
分子别名（Synonym）
GLP-1, GLP-1-R, GLP-1R, glucagon like peptide 1 receptor
表达区间及表达系统（Source）
Human GLP1R Protein, Flag,His Tag (GLR-H52D5) is expressed from human 293 cells (HEK293). It contains AA Arg 24 - Ser 432 (Accession # P43220-1).
Predicted N-terminus: Met
蛋白结构（Molecular Characterization）
This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus.
The protein has a calculated MW of 67.0 kDa.
制剂（Formulation）
Please contact us for detailed information.
Contact us for customized product form or formulation.
运输（Shipping）
This product is supplied and shipped with dry ice, please inquire the shipping cost.
存储（Storage）
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- The product MUST be stored at -70°C or lower upon receipt;
- -70°C for 3 months under sterile conditions.
背景（Background）
This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke.
