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 >  Protein>FCRL5 >FC5-M52H3

Mouse FCRL5 Protein, His Tag, low Endotoxin (MALS verified)

分子别名(Synonym)

BXMAS1, CD307, CD307e, FCRH5, IRTA2, PRO820

表达区间及表达系统(Source)

Mouse FCRL5 Protein, His Tag (FC5-M52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Ala 496 (Accession # NP_899045).

Predicted N-terminus: Gln 27

Request for sequence

蛋白结构(Molecular Characterization)

FCRL5 Structure

This protein carries a polyhistidine tag at the C-terminus

The protein has a calculated MW of 54.5 kDa. The protein migrates as 65-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 0.01 EU per μg by the LAL method.

纯度(Purity)

>90% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

FCRL5 SDS-PAGE

Mouse FCRL5 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS

FCRL5 SEC-MALS

The purity of Mouse FCRL5 Protein, His Tag (Cat. No. FC5-M52H3) is more than 90% and the molecular weight of this protein is around 55-75 kDa verified by SEC-MALS.

Report

 

背景(Background)

Fc Receptor-Like 5 (FCRL5), also known as FcRH3 (FcRH5 in human), IRTA2, and CD307e, is a 90 ‑ 95 kDa member of the FCRL family of proteins whose amino acid (aa) sequence is reminiscent of that for classical Fc receptors. FCLR molecules are type 1 transmembrane proteins that contain from three to nine immunoglobulin-like domains. They are differentially expressed within the B cell lineage, and can either promote or inhibit B cell proliferation and activation

 

前沿进展

 
 
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FCRL5靶点信息
英文全称:Fc receptor-like protein 5
中文全称:Fc受体样蛋白5
种类:
上市药物数量:0详情
临床药物数量:2详情
最高研发阶段:临床二期
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