膜杰作
Star Staining
描述/背景（Background）
CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
种属（Host Species）
Mouse
克隆号（Clone）
5G4
适用方法（Application）
IHC
效价（Property）
1：500
状态（State）
Liquid
阳性对照（Positive Control）
Human Tonsil Tissues
克隆类型（Clonality）
Monoclonal
分子别名（Synonym）
SDC1, Syndecan, SYND1, CD138
研究领域（Research Field）
Cancer Drug Targets
抗体来源（Source）
Mouse
同种型（Isotype）
IgG
储存（Storage）
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
典型数据（Typical Data）
质控样本（Control Sample）
Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S253 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
肿瘤样本（Cancer Sample）
Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S253 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
