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 >  Protein>CD7 >CD7-HA2H3

APC-Labeled Human CD7 Protein, His Tag (Site-specific conjugation)

分子别名(Synonym)

CD7,GP40,TP41,LEU-9,Tp40

表达区间及表达系统(Source)

APC-Labeled Human CD7 Protein, His Tag (CD7-HA2H3) is produced via conjugation of APC to Human CD7 Protein, His Tag with a new generation site-specific technology under optimal conditions with a proprietary technology. Human CD7 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Pro 180 (Accession # P09564-1).

Predicted N-terminus: Ala 26

Request for sequence

蛋白结构(Molecular Characterization)

CD7 Structure

This protein carries a polyhistidine tag at the C-terminus

The protein has a calculated MW of 20.0 kDa.

偶联(Conjugate)

APC

Excitation Wavelength: 640 nm

Emission Wavelength: 661 nm

应用说明(Application)

Please note that this product is NOT compatible to streptavidin detection system.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, 0.5% BSA, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

活性(Bioactivity)-FACS

CD7 FACS

5e5 of anti-CD7 CAR-293 cells were stained with 100 μL of 1:25 dilution (4 μL stock solution in 100 μL FACS buffer) of APC-Labeled Human CD7 Protein, His Tag (Cat. No. CD7-HA2H3) and negative control protein respectively. APC signal was used to evaluate the binding activity (QC tested).

Protocol

 

背景(Background)

T-cell antigen CD7 (CD7) is also known as GP40, LEU-9, TP41 and Tp40. CD7 is a protein that in humans is encoded by the CD7 gene, this gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. CD7 has been shown to interact with PIK3R1. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.

 

前沿进展

 
 
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CD7靶点信息
英文全称:T-cell antigen CD7
中文全称:T细胞抗原CD7
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:24详情
最高研发阶段:临床二期
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