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 >  Antibody>CD45R >HGS-S248

Recombinant Monoclonal Anti-CD45R Antibody, Mouse (4C4)

描述/背景(Background)

CD45R (PTPRC) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. CD45 is specifically expressed in hematopoietic cells and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling.

种属(Host Species)

Mouse

克隆号(Clone)

4C4

适用方法(Application)

IHC

效价(Property)

1:500

状态(State)

Liquid

阳性对照(Positive Control)

Human Tonsil Tissues

克隆类型(Clonality)

Monoclonal

分子别名(Synonym)

CD45R

研究领域(Research Field)

Cancer Drug Targets

抗体来源(Source)

Mouse

同种型(Isotype)

IgG

储存(Storage)

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

 

典型数据(Typical Data)

质控样本(Control Sample)

CD45R CONTROL SAMPLE

Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S248 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

肿瘤样本(Cancer Sample)

CD45R CANCER SAMPLE

CD45R CANCER SAMPLE

CD45R CANCER SAMPLE

Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S248 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

 

前沿进展

 
 
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CD45R靶点信息
英文全称:Leukocyte common antigen
中文全称:白细胞共同抗原
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:3详情
最高研发阶段:临床三期
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