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HEK293/Human TrkB Stable Cell Line

For research use only.
此产品为在研产品。如果您对此产品有兴趣,请直接联系我们。我们会根据您的需求相应地加速我们的研发进程,并为您进行产品预留。

描述(Description)

HEK293/Human TrkB Stable Cell Line

应用说明(Application)

Binding assay by FACS and cell based ELISA.

生长特性(Growth Properties)

Adherent

筛选标记(Selection Marker)

Hygromycin B (150 μg/mL)

培养基(Culture Medium)

DMEM medium + 10% FBS

冻存液(Freeze Medium)

10% DMSO + 90% FBS

装量(Quantity)

1 vial contains at least 5×10^6 cells in 1 mL serum-free cryopreservation medium

存储(Storage)

Frozen in liquid nitrogen.

使用说明(Instructions for Use)

See data sheet for detailed culturing and assay protocol.

 

背景(Background)

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

 

License Disclosure

This cell line is provided for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make this cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit modification of this cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license. Modifications of this cell line, transfer to another facility, or commercial use of the cell lines may require a separate license and additional fees. AcroBiosystems does not warrant the suitability of this cell line for any particular use, and does not accept any liability in connection with the handling or use of this cell line.

 

前沿进展

 
 
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TrkB靶点信息
英文全称:Neurotrophic tyrosine kinase receptor type 2
中文全称:神经营养性酪氨酸激酶受体-2型
种类:Homo sapiens
上市药物数量:3详情
临床药物数量:7详情
最高研发阶段:批准上市
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