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 >  Protein>Cadherin-3 >CA3-H52H3

Human Cadherin-3 Protein, His Tag

分子别名(Synonym)

CDH3,CDHP,Cadherin-3,P-cadherin

表达区间及表达系统(Source)

Human Cadherin-3, His Tag (CA3-H52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 108 - Gly 654 (Accession # P22223-1).

Predicted N-terminus: Asp 108

Request for sequence

蛋白结构(Molecular Characterization)

Online(Asp 108 - Gly 654) P22223-1

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 61.9 kDa. The protein migrates as 70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>90% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Human Cadherin-3, His Tag (Cat. No. CA3-H52H3) SDS-PAGE gel

Human Cadherin-3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

背景(Background)

Cadherin-3 (also known as P-cadherin)is a classical cell-to-cell adhesion molecule with a homeostatic function in several normal tissues. In humans, cadherin-3 is only detected in a few organs. However, its overexpression is strongly associated with a poor prognosis in some solid tumors including breast, lung and pancreatic cancers.

 

 

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Cadherin-3靶点信息
英文全称:Cadherin 3
中文全称:钙粘附蛋白3
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:6详情
最高研发阶段:临床二期
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