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CA125信息

英文名称:Mucin-16
中文名称:粘蛋白-16
靶点别称:Mucin-16,CA125,Ovarian carcinoma antigen CA125,CA-125,MUC16,MUC-16,Ovarian cancer-related tumor marker CA125
上市药物数量:0
临床药物数量:5
最高研发阶段:撤市

CA125产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
CA5-H82F4
Human
Biotinylated Human CA125 / MUC16 Protein, Fc,Avitag
 
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CA125 Molecule Synonym Name

CA125,CA-125,CA125MUC-16,FLJ14303,MUC16,mucin 16,mucin-16

CA125 分子背景

The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

CA125 参考文献

CA125临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
RG-7882 RG-7882; D-4064A; DMUC-4064A 临床一期 基因泰克 卵巢癌, 胰腺癌 详情
Igovomab 撤市 CIS bio international 卵巢癌
Oregovomab B43.13 临床二期 Paladin Pharma, 美国国立癌症研究所, Quest PharmaTech, University of Nebraska Medical Center 卵巢癌, 胰腺癌 详情
Sofituzumab vedotin RG-7458; DMUC-5754A 临床一期 基因泰克 输卵管癌, 腹膜癌, 卵巢癌, 胰腺癌 详情
JCAR-020 JCAR-020 临床一期 斯隆-凯特琳癌症中心, Juno Therapeutics 卵巢癌 详情

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