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BTLA信息

英文名称:B- and T-lymphocyte attenuator
中文名称:B和T淋巴细胞衰减因子
靶点别称:B- and T-lymphocyte attenuator,B- and T-lymphocyte-associated protein,B And T Lymphocyte Associated,CD272 Antigen,BTLA1,CD272,BTLA
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

BTLA Molecule Synonym Name

BTLA,CD272

BTLA 分子背景

B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.

BTLA 参考文献

BTLA临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
JS004 JS-004; TAB-004 临床一期 上海君实生物医药科技股份有限公司 实体瘤, 肾细胞癌, 移行细胞癌, 淋巴瘤, 黑色素瘤 详情

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