BTLA 靶点蛋白|抗体药物|临床药物信息

BTLA信息

英文名称：B- and T-lymphocyte attenuator
中文名称：B和T淋巴细胞衰减因子
靶点别称：B- and T-lymphocyte attenuator，B- and T-lymphocyte-associated protein，B And T Lymphocyte Associated，CD272 Antigen，BTLA1，CD272，BTLA

上市药物数量：0
临床药物数量：1
最高研发阶段：临床一期

BTLA产品列表

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产品库

在线 (9)

物种

标签

属性

Protein (9)

标记

货号	物种	产品描述
BTA-H5255	Human	Human BTLA /CD272, With C-Fc Tag
BTA-H5256	Human	Human BTLA (31-150) Protein, Fc Tag
BTA-H52E0	Human	Human BTLA Protein, His Tag
BTA-M52E2	Mouse	Mouse BTLA Protein, His Tag
BTA-M5253	Mouse	Mouse BTLA Protein, Fc Tag
BTA-H82F8	Human	Biotinylated Human BTLA (31-134) Protein, Fc,Avitag
BTA-H82F3	Human	Biotinylated Human BTLA (31-150) Protein, Fc,Avitag
BTA-H82E6	Human	Biotinylated Human BTLA (31-150) Protein, His,Avitag
BTA-H5258	Human	Human BTLA (31-150) Protein, Mouse IgG2a Fc Tag

BTLA Molecule Synonym Name

BTLA,CD272

BTLA 分子背景

B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.

BTLA 参考文献

BTLA临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
JS004	JS-004; TAB-004	临床一期	上海君实生物医药科技股份有限公司	实体瘤, 肾细胞癌, 移行细胞癌, 淋巴瘤, 黑色素瘤	详情

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BTLA 重组蛋白