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Rat LAG3 / CD223 Protein, His Tag

分子别名(Synonym)

LAG3,CD223,FDC

表达区间及表达系统(Source)

Rat LAG3, His Tag (LA3-R52H5) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Leu 442 (Accession # NP_997678).

Predicted N-terminus: Gly 24

蛋白结构(Molecular Characterization)

Online(Gly 24 - Leu 442) NP_997678

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 47.6 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>90% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Rat LAG3, His Tag (Cat. No. LA3-R52H5) SDS-PAGE gel

Rat LAG3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

背景(Background)

Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

 

前沿进展

 
货号/价格

LA3-R52H5-100ug / ¥2900

LA3-R52H5-1mg (100ug X 10) / ¥19800

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LAG-3靶点信息
英文全称:Lymphocyte activation gene 3 protein
中文全称:淋巴细胞活化基因3蛋白
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:18详情
最高研发阶段:临床三期
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