登录 | 注册    关注公众号  
微信公众号
搜索
 > 【Integrin alpha 10 beta 1】

Integrin alpha 10 beta 1信息

英文名称:Integrin alpha10/beta1
中文名称:整合素α-10/β-1复合体
靶点别称:Integrin alpha-10/Integrin beta-1,Integrin alpha-10/beta-1
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

Integrin alpha 10 beta 1分子别名

Integrin alpha 10 beta 1,ITGA10&ITGB1

Integrin alpha 10 beta 1分子背景

Human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types I-VI and laminin-1 in a Mg(2+)-dependent manner, whereas its binding to tenascin was only slightly better than to albumin. Alpha 10 beta 1 is a known collagen-binding I domain integrin, in addition to α1β1, α2β1 and α11β1. GROGER found in the N-terminal domain of collagens I and III, is only weakly recognised by α10β1, an important collagen receptor on chondrocytes, contrasting with the other collagen-binding integrins.

消息提示

请输入您的联系方式,再点击提交!

确定