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 > 【Tau-441】重组蛋白信息

Tau-441产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
TAU-H51H3
Human
Human Tau-441 / 2N4R Protein, His Tag
 
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Tau-441 Molecule Synonym Name

DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU

Tau-441 分子背景

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies. Tau-441 is known as "2N4R," "Isoform Tau-F," "Tau-4" or "Tau 441", which consisting of 441 amino acid. Tau-441 is a potential therapeutic target for pathogenesis.

Tau-441 参考文献

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