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 > 【B7-H7】重组蛋白信息

B7-H7产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
B77-H82F5
Human
Biotinylated Human B7-H7 / HHLA2 Protein, Fc,Avitag
B77-H52H5
Human
Human B7-H7 / HHLA2 Protein, His Tag
B77-H5257
Human
Human B7-H7 / HHLA2 Protein, Fc Tag
 
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B7-H7 分子别名

B7-H7,HHLA2,B7 Homolog 7

B7-H7 分子背景

B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.

B7-H7 参考文献

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