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 > 【B7-H6】重组蛋白信息

B7-H6产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
B76-H82E5
Human
Biotinylated Human B7-H6 / NCR3LG1 Protein, His,Avitag
B76-H52H8
Human
Human B7-H6 / NCR3LG1 Protein, His Tag
B76-C52Ha
Cynomolgus
Cynomolgus B7-H6 / NCR3LG1 Protein
 
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B7-H6 分子别名

B7-H6,NCR3LG1,B7 Homolog 6

B7-H6 分子背景

The B7 family of genes is essential in the regulation of the adaptive immune system. one of which is the recently discovered B7H6. Humans and rats have a single B7H6 gene; however, many B7H6 genes were detected in a single large cluster in the Xenopus genome. Chimeric antigen receptor (CAR) T-cell therapies have demonstrated durable and potentially curative therapeutic efficacy against B-cell leukemia in clinical trials. In this study, B7H6, a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues.

B7-H6 参考文献

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