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IL-12B & IL-12A产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
IL2-H4210
Human
Human IL-12B&IL-12A Heterodimer Protein, His Tag&Flag Tag
 
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IL-12B & IL-12A 分子别名

IL12,p70,Interleukin-12

IL-12B & IL-12A 分子背景

Interleukin 12 (IL12) is also known as p70, and is an interleukin that is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.IL12 is a heterodimeric cytokine, containing IL-12A (p35) and IL-12B (p40). IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-γ and TNF-α from T cells and NK cells, and reduces IL-4 mediated suppression of IFN-γ. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 also has anti-angiogenic activity, which means it can block the formation of new blood vessels.

IL-12B & IL-12A 参考文献

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