IL23A & IL12B 靶点蛋白|抗体药物|临床药物信息

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Protein (5)

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货号	物种	产品描述
ILB-H52W5	Human	Human IL-23 alpha&IL-12 beta Heterodimer Protein, His Tag&Tag Free
ILB-HM52W6	Human & Mouse	Human IL-23 alpha & Mouse IL-12 beta Heterodimer Protein, His Tag&Tag Free
ILB-M52W7	Mouse	Mouse IL-23 alpha&IL-12 beta Heterodimer Protein, His Tag&Tag Free
ILB-H82W6	Human	Biotinylated Human IL-23 alpha&IL-12 beta Heterodimer Protein, His,Avitag&Tag Free
ILB-CM52W8	Cynomolgus & Mouse	Cynomolgus IL-23 alpha & Mouse IL-12 beta Heterodimer Protein, His Tag&Tag Free

IL23A & IL12B Molecule Synonym Name

IL-23 alpha & IL-12 beta

IL23A & IL12B 分子背景

Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

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IL23A & IL12B 重组蛋白

IL23A & IL12B产品列表

IL23A & IL12B Molecule Synonym Name

IL23A & IL12B 分子背景

IL23A & IL12B 参考文献

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