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HSP90AA1信息

英文名称:Heat shock protein HSP 90-alpha
中文名称:热休克蛋白90α家族A类成员1
靶点别称:HSP90A ,HSPCA,Heat shock 86 kDa,HSP86,Renal carcinoma antigen NY-REN-38,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,LAP-2,HSP90AA1,HSPC1,Heat shock protein HSP 90-alpha,HSP 86
上市药物数量:0
临床药物数量:1
最高研发阶段:临床三期

HSP90AA1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
HS1-H513x
Human
Human HSP90AA1 / HSP 90-alpha Protein, with N-GST Tag
 
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HSP90AA1 分子别名

HSP90AA1,HSP90A,HSP 86,HSP86,HSPC1,HSPCA,EL52,HSP89A,HSP90N,HSPCAL1,HSPCAL4,HSPN,Hsp89,Hsp90,LAP2

HSP90AA1 分子背景

Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

HSP90AA1 参考文献

HSP90AA1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
TAS-116 TAS-116,TAS116 临床三期 大鹏药品, 大冢制药 胃肠道间质瘤 详情

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